PRREP prepares residents for careers in research

Washington University School of Medicine has consistently been ranked as a top 10 research university with a mean rank in NIH funding of 4.1. For those residents interested in exploring research, we are able to provide outstanding research mentors from an internationally recognized faculty.

Faculty mentorship

One of the keys to a successful academic career is a knowledgeable faculty mentor. Our expert faculty take pride in developing quality interactions with trainees and routinely produce more than 300 publications each year, usually co-authored with trainees.  These papers make an impact with other researchers, at a median faculty h-index of 22.5. Faculty are well-connected nationally and internationally with service to various committees and panels. These connections are important as trainees begin to navigate their independent careers.

Faculty from other departments are also available to serve as research and career mentors to our residents. There are over 150 faculty at Washington University in St. Louis who conduct research in areas relevant to psychiatric disorders including cellular and molecular neuroscience, neurology, psychology, psychiatry, anesthesiology, genetics, epidemiology, and public health.

Research training opportunities

During residency

Residents interested in an academic research career can participate in our Psychiatry Residency Research Education Program (PRREP). Residents who do not wish to pursue such an intensive research experience may select research for one or both of their selective blocks during PGY2 or for any of their 4 months of their PGY4 elective time.

After residency

Residents desiring a more intensive exposure to research after residency may be able to participate in one or more additional years of research training as a research fellow.

Psychiatry Residency Research Education Program (PRREP)

The Psychiatry Residency Research Education Program (PRREP) seeks to provide early training in research to enhance success at subsequent stages of residents’ careers.  PRREP represents formalized research mentorship to those residents interested in research.

This program is open to any resident, regardless of prior research experience. Whether you’re an MD/PhD with lots of research experience or you didn’t do much research during medical school, we tailor our program to develop and maximize your individual skills.

Most residents typically will choose to take part in the program starting in the first year of residency. It is expected that some trainees, as they explore research, will not pursue the more advance PRREP phase. Funds (up to $25K total during residency training) are available to support research and travel costs through an NIH R25 grant.

PRREP structure

PRREP has been structured to provide a longitudinal research training experience across all years to individuals in both the general adult psychiatry program (4 years) and the child and adolescent psychiatry program (5 years). The program is composed of two phases.

Phase 1: Exploration

The first phase of PRREP occurs during PGY1 and 2 and is designed to allow residents to explore the possibility of research as a career option.

In addition to mentoring and didactic time, residents will devote 2 PGY2 elective blocks (approximately 2 months) to research.

For those residents with substantial research experience (e.g. MD/PhD), the available PRREP time is used to begin their formal research projects during this exploration phase.

PGYTime on
Research
Rotations
Didactics, Courses, MeetingsMilestones
1Monthly advisor and/or mentor meetings

Weekly department research conference

10-hour research seminar
Identify research mentor

Create career development goals

Create PGY2 research proposal
216% FTEMentor Meetings

Weekly research conference

12-hour research course

Individualized coursework
Work on initial career development goals

Carryout PGY2 research

Develop initial Phase 2 research proposal

Phase 2: In-depth training

The second phase is a more intensive program that begins in PGY3 and runs the rest of residency training. It is designed for those residents who, after Phase 1, have decided to continue pursuing a career in academic psychiatry.

This second phase provides for in-depth training in research, including a formal research project, career mentoring, and didactics. Residents will have 15% of their third year dedicated to research efforts.

PGYTime on
Research
Rotations
Didactics, Courses, MeetingsMilestones
315% FTEMentor meetings

Weekly research conference

PRREP research seminar

Individualized coursework
Modify career development goals and research proposal by end of PGY3
Adult Residents

Residents staying in the general adult program will then have 8 months of their PG4 year to finish carrying out their research projects. In total, adult residents will have approximately 12 months of hands-on research time over the four years.

PGYTime on
Research
Rotations
Didactics, Courses, MeetingsMilestones
467% FTEMentor meetings

Weekly research conference

Leadership course

Individualized coursework
Present results at poster and oral sessions

Publication/presentation of results at meetings
Child & Adolescent Psychiatry Fellows

Residents who decide to pursue training in child and adolescent psychiatry at Washington University can continue to be in PRREP and will have approximately 10 months of dedicated research time spread over their two CAP training years.

PGYTime on
Research
Rotations
Didactics, Courses, MeetingsMilestones
430% FTEMentor meetings

Weekly research conference

Leadership course

Individualized coursework
Modify career and research goals as needed
550% FTEMentor meetings

Weekly research conference

Individualized coursework
Present results at poster and oral sessions

Publication/presentation of results at meetings

Joining PRREP

PRREP is not a specific training track (with a separate ACGME program number) to which applicants must apply prior to joining our program. Rather, it is a training path available to any resident in our program. Such an approach allows for us to train more than just the 1 or 2 residents that other research track programs typically can accommodate. It also does not force applicants to choose prior to residency training what type of career they will have. Instead it is designed to be flexible and to allow residents to explore the possibility of a career in research prior to committing to that career pathway.

Residents typically request to join Phase 1 of PRREP in their first year so that they can have the time to meet with a mentor and optimally plan for their second year research rotations. There is no maximum number of residents that can take part in PRREP, nor is there a minimum educational requirement. Historically, approximately ⅓-⅔ of the interns join PRREP each year.

Residents opting to continue into Phase 2 submit a detailed research and career development plan, which has to be approved by the supervising faculty before entering into Phase 2.

Applicants to the residency program who are interested in PRREP are encouraged to indicate such interest at the time they apply so that we can be prepared to discuss the interest during the interview process.

Mentorship in PRREP

We have created a core group of faculty advisors and mentors whom the majority of participants will likely use for their training. Each PRREP resident begins working with one of these individuals during Phase 1 in order to identify an area of research interest and a research project.

Trainees might also use one of over 150 university faculty members who have significant research experience and extramural support in the broad areas of research relevant to psychiatry as a co-mentor in whose lab they will conduct research. These areas of research include cellular and molecular neuroscience, neurology, psychology, psychiatry, anesthesiology, genetics, epidemiology, and public health.

Faculty

Department

Group

Arpana AgrawalPsychiatryGenetics*
Deanna BarchPsychologyImaging
Laura BierutPsychiatryGenetics
Kevin BlackPsychiatryImaging
Patty Cavazos-RehgPsychiatryGenetics
Carlos CruchagaPsychiatryGenetics
Joseph DoughertyGeneticsBasic
Andrew HeathPsychiatryGenetics
Tamara HersheyPsychiatryImaging
Adam KepecsNeuroscienceBasic
Eric LenzePsychiatryClinical
Joan LubyPsychiatryClinical
Jordan McCallAnesthesiologyBasic
Steven MennerickPsychiatryBasic
Ben PalancaAnesthesiologyClinical
Susan PerlmanPsychiatryClinical
John PruettPsychiatryImaging
Cynthia RogersPsychiatryClinical
Chad SylvesterPsychiatryImaging
Charles ZorumskiPsychiatryBasic

*Human Genetics, Public Health, Epidemiology

PRREP Outcomes

The mentoring and structure of PRREP creates a strong academic ethos in our training program that has allowed our residents to thrive.  Their accomplishments have been amazing. In addition to winning awards and presenting their work at national and international meetings they have co-authored a very large number of research articles.  Since its inception in 2016, our PRREP residents have been authors on over 100 publications. Of the 22 residents who have finished the PRREP program 16 have opted for a career in academic psychiatry with the vast majority choosing to undergo extensive research training via a T32 training grant mechanism.  

PRREP resident, Joshua Hill, presenting his research to NIDA deputy director and WUSM alumnus, Wilson Compton, at the April 2024 American Society of Addiction Medicine (ASAM) meeting