Division of Basic Science Research

This division focuses on understanding mechanisms of brain function and behavior in the context of psychiatric disease.

Division Director

Alexxai Kravitz

Associate Professor of Psychiatry

• Phone: 314-273-7956
• Email: alexxai@nospam.wustl.edu

Faculty

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Muhammad Ali

Assistant Professor of Psychiatry

• Phone: 774-823-8562
• Email: m.ali@wustl.edu

Anil Cashikar

Associate Professor of Psychiatry

• Phone: 314-273-1863
• Email: cashikar@wustl.edu

Carlos Cruchaga

Barbara Burton & Reuben Morriss III Professor

• Phone: 314-286-0546
• Email: cruchagac@wustl.edu

Abdallah El-Thaileb (Eteleeb)

Assistant Professor of Psychiatry

• Phone: 314-273-1560
• Email: eteleeb@wustl.edu

Laura Ibanez

Assistant Professor of Psychiatry

• Phone: 314-273-3641
• Email: ibanezl@wustl.edu

Sayaka Inoue

Assistant Professor of Psychiatry

• Phone: 314-362-3142
• Email: sayaka@wustl.edu

Abhi Iyer

Assistant Professor of Psychiatry

• Phone: 314-362-8745
• Email: iyera@wustl.edu

Yukitoshi Izumi

Professor of Psychiatry

• Phone: 314-747-2987
• Email: izumiy@wustl.edu

Celeste Karch

Barbara Burton and Reuben M Morriss III Professorship

• Phone: 314-747-3161
• Email: karchc@wustl.edu

Alexxai Kravitz

Associate Professor of Psychiatry

• Phone: 314-273-7956
• Email: alexxai@wustl.edu

Federica Lucantonio

Assistant Professor of Psychiatry

• Phone: 314-940-6031
• Email: federica@wustl.edu

Susan Maloney

Associate Professor of Psychiatry

• Phone: 314-940-6008
• Email: maloneys@wustl.edu

Dario Maschi

Assistant Professor of Psychiatry

• Phone: 314-362-5518
• Email: dario.maschi@wustl.edu

Steven Mennerick

John P Feighner Professor of Neuropsychopharmacology

• Phone: 314-747-2988
• Email: menneris@wustl.edu

Miguel Minaya

Assistant Professor of Psychiatry

• Phone: 314-273-8145
• Email: miguel.minaya@wustl.edu

Kevin Noguchi

Associate Professor of Psychiatry

• Phone: 314-362-7007
• Email: noguchik@wustl.edu

Marco Pignatelli

Assistant Professor of Psychiatry

• Phone: 314-273-3733
• Email: marco.pignatelli@wustl.edu

Hongjin Shu

Assistant Professor of Psychiatry

• Phone: 314-362-8658
• Email: shuh@wustl.edu

Current Research Publications

• A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a model of frontotemporal dementia
  November 30, 2026
  A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a model of frontotemporal dementiaMirfakhar, F. S., Marsh, J. A., Sato, C., Schache, K. J., Minaya, M. A., Dolle, R. E., Pak, S. C., Silverman, G. A., Perlmutter, D. H., Macauley, S. L. & Karch, C. M., Dec 2026, In: Nature communications. 17, 1, 2699.Research output: Contribution to journal › Article › peer-review
• Association of LRRK2 p.A419V with Parkinson’s Disease in East Asians and analysis of age at onset
  November 30, 2026
  Association of LRRK2 p.A419V with Parkinson’s Disease in East Asians and analysis of age at onsetthe Global Parkinson’s Genetics Program (GP2), Dec 2026, In: npj Parkinson's Disease. 12, 1, 51.Research output: Contribution to journal › Article › peer-review
• OMG! A proteomic determinant of neurodegenerative resiliency
  November 30, 2026
  OMG! A proteomic determinant of neurodegenerative resiliencyDuggan, M. R., Oh, H. S. H., Frank, P., Gomez, G. T., Zweibaum, D., Cui, Y., Chen, J., Surapaneni, A., Blew, C. O., Dark, H. E., Joynes, C. M., Kandala, S., Bilgel, M., Farinas, A., Erus, G., Tian, Q., Candia, J., Pucha, K. A., Landman, B. A. & Dumitrescu, L. & 36 others, Hohman, T. J., Lewis, A., Moghekar, A., Siavoshi, F., Ali, M., Liu, M., Xu, Y., Western, D., Kaneko, N., Kato, S., Furuichi, M., Shibayama, M., Katsuno, M., Nishita, Y., Otsuka, R., Gottesman, R. F., Dammer, E. B., Seyfried, N. T., Levey, […]
• Antecedent enhancer activity predicts future susceptibility to seizures in mice
  November 30, 2026
  Antecedent enhancer activity predicts future susceptibility to seizures in miceBoros, B. D., Gachechiladze, M. A., Guo, J., Galloway, D. A., Mueller, S. M., Shabsovich, M., Yen, A., Chen, X., Cammack, A. J., Shen, T., Mitra, R. D., Dougherty, J. D. & Miller, T. M., Dec 2026, In: Nature communications. 17, 1, 300.Research output: Contribution to journal › Article › peer-review
• Structure-activity relationships of steroid and sterol neuromodulators on inflammatory markers in a murine microglial cell line
  April 30, 2026
  Structure-activity relationships of steroid and sterol neuromodulators on inflammatory markers in a murine microglial cell lineShu, H. J., Covey, D. F., Zorumski, C. F. & Mennerick, S., May 2026, In: Journal of Steroid Biochemistry and Molecular Biology. 259, 106969.Research output: Contribution to journal › Article › peer-review