| 1955-1971 | Dr. George Winokur |
| 1971-1974 | Dr. Richard Hudgens |
| 1974-1976 | Dr. Robert Woodruff |
| 1976-1979 | Dr. Amos Welner |
| 1979-1985 | Dr. John Helzer; Dr. John Knesevich was the assistant residency director from 1981-1985. |
| 1985-1987 | Dr. John Knesevich |
| 1987-2007 | Dr. Eugene Rubin; over these twenty years, Drs. Stephen Dinwiddie, Wilson Compton and Nuri Farber were assistant residency directors. |
| 2007- current | Dr. Nuri Farber; Dr. Melissa Harbit is the assistant residency director. In 2022, Dr. Harbit became associate residency director, and Dr. Matthew Chapman became assistant residency director. |