Additional Titles & Roles
- Member, The Division of Biology and Biomedical Sciences (DBBS), Neuroscience Program
Education & Training
- Postdoctoral Training: Washington University, St. Louis, MO, 2007
- Fellowship: Child & Adolescent Psychiatry: Washington University, St. Louis, MO, 2005
- Residency: Washington University, St. Louis, MO, 2003
- MD: Washington University, St. Louis, MO, 2000
- PhD: Neuroscience: Washington University, St. Louis, MO, 2000
- BA: Princeton University , Princeton, NJ,
Major Awards
- Recognition for Hazlett et al., 2017 (role: middle author): Spectrum’s “Notable papers in autism research in 2017″, 2017
- Autism Speaks’ “Top Ten 2017 Studies”, 2017
- Autism Science Foundation’s “The Big News This Year: Biology Before Behavior”, 2017
- Selected NICHD Research Advances, 2017
- Back-Up Chair, NIH Developmental Brain Disorders (DBD) Study Section, 2017, 2018
- Chartered Member, NIH Developmental Brain Disorders (DBD) Study Section, 2016
Areas of Clinical Interest
-Autism Spectrum Disorder (ASD): early diagnosis (age 1-3)
Research Interests
-The neuroscience of ASD, social cognition and comparative cognition
Key Publications
- Marrus N, Eggebrecht AT, Todorov A, Elison JT, Wolff JJ, Cole L, Gao W, Pandey J, Shen MD, Swanson MR, Emerson RW, Klohr CL, Adams CM, Estes AM, Zwaigenbaum L, Botteron KN, McKinstry RC, Constantino JN, Evans AC, Hazlett HC, Dager SR, Paterson SJ, Schultz RT, Styner MA, Gerig G, , Schlaggar BL, Piven J*, Pruett JR Jr*, (2018 Feb). Walking, Gross Motor Development, and Brain Functional Connectivity in Infants and Toddlers. Cereb. Cortex. 28(2): 750-763.
*Co-senior authors
Read publication »Walking, Gross Motor Development, and Brain Functional Connectivity in Infants and Toddlers. - Emerson RW, Adams C, Nishino T, Hazlett HC, Wolff JJ, Zwaigenbaum L, Constantino JN, Shen MD, Swanson MR, Elison JT, Kandala S, Estes AM, Botteron KN, Collins L, Dager SR, Evans AC, Gerig G, Gu H, McKinstry RC, Paterson S, Schultz RT, Styner M, , Schlaggar BL, Pruett JR Jr*, Piven J*, (2017 Jun). Functional neuroimaging of high-risk 6-month-old infants predicts a diagnosis of autism at 24 months of age. Sci Transl Med. 9(393):
*Co-senior authors
Read publication »Functional neuroimaging of high-risk 6-month-old infants predicts a diagnosis of autism at 24 months of age. - Shaw JA, Bryant LK, Malle BF, Povinelli DJ, Pruett JR Jr, (2017 Apr). The relationship between joint attention and theory of mind in neurotypical adults. Conscious Cogn. 51: 268-278.
Read publication »The relationship between joint attention and theory of mind in neurotypical adults. - Eggebrecht AT, Elison JT, Feczko E, Todorov A, Wolff JJ, Kandala S, Adams CM, Snyder AZ, Lewis JD, Estes AM, Zwaigenbaum L, Botteron KN, McKinstry RC, Constantino JN, Evans A, Hazlett HC, Dager S, Paterson SJ, Schultz RT, Styner MA, Gerig G, Das S, Kostopoulos P, Schlaggar BL, Petersen SE, Piven J*, Pruett JR Jr*, (2017 Mar). Joint Attention and Brain Functional Connectivity in Infants and Toddlers. Cereb. Cortex. 27(3): 1709-1720.
*Co-senior authors
Read publication »Joint Attention and Brain Functional Connectivity in Infants and Toddlers. - Pruett JR Jr, Povinelli DJ, (2016 Dec). Commentary – Autism Spectrum Disorder: Spectrum or Cluster? Autism Res. 9(12): 1237-1240.
Read publication »Commentary – Autism Spectrum Disorder: Spectrum or Cluster? - Pruett JR Jr, Kandala S, Hoertel S, Snyder AZ, Elison JT, Nishino T, Feczko E, Dosenbach NU, Nardos B, Power JD, Adeyemo B, Botteron KN, McKinstry RC, Evans AC, Hazlett HC, Dager SR, Paterson S, Schultz RT, Collins DL, Fonov VS, Styner M, Gerig G, Das S, Kostopoulos P, Constantino JN, Estes AM, , Petersen SE, Schlaggar BL, Piven J, (2015 Apr). Accurate age classification of 6 and 12 month-old infants based on resting-state functional connectivity magnetic resonance imaging data. Dev Cogn Neurosci. 12: 123-33.
Read publication »Accurate age classification of 6 and 12 month-old infants based on resting-state functional connectivity magnetic resonance imaging data.
Funded Research Projects
ACTIVE:
R01 (2R01) HD055741-11 (NICHD) (Piven, PI) 9/7/17-7/31/22
“A Longitudinal Brain and Behavior Study of Autism from Infancy through School Age” (fcMRI Imaging Processing Core)
This study is a competing continuation of an Autism Center of Excellence (ACE) Network grant supporting a prospective, longitudinal examination of brain and behavior at 3, 6, 9, 12, 15 and 24 months in infants at high familial risk (HR) and low risk (LR) for autism.
Role: Sub-Contract PI
1 U54 HD087011-01 (NICHD) (Constantino and Schlaggar, Co-PIs) 9/18/15 – 5/31/20
“Sex-Specific Modulation of ASD Liability: Compensatory Mechanisms and Recurrence”
The Intellectual and Developmental Disabilities Research Center at the Washington University School of Medicine is a scientific program composed of three core facilities, one dedicated to studies of cellular and molecular mechanisms of causation in IDD, one dedicated to the identification of “signatures” of developmental disability that can be imaged in the developing brain, and one dedicated to in-depth clinical assessment of human subjects and the translation of new understanding of causal mechanisms into higher impact intervention.
Role: Co-Investigator
WUIDDRC Pilot Fund (Pruett, PI) 5/27/16 – 5/26/17
“Toddler social motivation and communication”
The scientific objective of this study is to correlate dimensional measures of joint attention with ASD-relevant abilities.
Role: PI
The Drs. John R. (Sr.) and Patricia O. Pruett Fund for research in social cognition and for undergraduate training
The Azrieli Neurodevelopmental Research Program/ Brain Canada Multi-Investigator Research Initiative (A. Evans, PI) 4/1/14-3/31/19 “Structural and Functional Networks in Autism Spectrum Disorder and Fragile X Syndrome”
Role: Mentor/Collaborator
R01 MH104543 (NIMH) (L. Parr, PI)
“Effects of Oxytocin on Brain, Behavior, and Development” 5/1/15-4/30/20.
This project will examine the effects of repeated oxytocin administration on social behavior and neural development in infant monkeys as a first step towards understanding how this hormone modulates social behavior.
Role: Consultant