Division of Basic Science Research

This division focuses on understanding mechanisms of brain function and behavior in the context of psychiatric disease.

Division Director

Alexxai Kravitz

Associate Professor of Psychiatry

• Phone: 314-273-7956
• Email: alexxai@nospam.wustl.edu

Faculty

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Kevin Noguchi

Associate Professor of Psychiatry

• Phone: 314-362-7007
• Email: noguchik@wustl.edu

Lari Niko-Petteri Nykanen

Instructor in Psychiatry

• Phone: 314-362-4476
• Email: nnykanen@wustl.edu

Steven Paul

Professor of Psychiatry

• Phone: 314-273-1863
• Email: smpaul@wustl.edu

Marco Pignatelli

Assistant Professor of Psychiatry

• Phone: 314-273-3733
• Email: marco.pignatelli@wustl.edu

Yun Ju Sung

Professor of Psychiatry

• Phone: 314-273-1967
• Email: yunju@wustl.edu

Carla Yuede

Professor of Psychiatry

• Phone: 314-362-9001
• Email: yuedec@wustl.edu

Charles Zorumski

Samuel B. Guze Professor of Psychiatry

• Phone: 314-747-2680
• Email: zorumskc@wustl.edu

Current Research Publications

• Characterization of early markers of disease in the mouse model of mucopolysaccharidosis IIIB
  December 1, 2024
  Characterization of early markers of disease in the mouse model of mucopolysaccharidosis IIIBMcCullough, K. B., Titus, A., Reardon, K., Conyers, S., Dougherty, J. D., Ge, X., Garbow, J. R., Dickson, P., Yuede, C. M. & Maloney, S. E., Dec 2024, In: Journal of neurodevelopmental disorders. 16, 1, 16.Research output: Contribution to journal › Article › peer-review
• Genetic and multi-omic resources for Alzheimer disease and related dementia from the Knight Alzheimer Disease Research Center
  December 1, 2024
  Genetic and multi-omic resources for Alzheimer disease and related dementia from the Knight Alzheimer Disease Research CenterFernandez, M. V., Liu, M., Beric, A., Johnson, M., Cetin, A., Patel, M., Budde, J., Kohlfeld, P., Bergmann, K., Lowery, J., Flynn, A., Brock, W., Sanchez Montejo, B., Gentsch, J., Sykora, N., Norton, J., Gentsch, J., Valdez, O., Gorijala, P. & Sanford, J. & 24 others, Sun, Y., Wang, C., Western, D., Timsina, J., Mangetti Goncalves, T., Do, A. N., Sung, Y. J., Zhao, G., Morris, J. C., Moulder, K., Holtzman, D. M., Bateman, R. J., Karch, C., Hassenstab, J., Xiong, C., Schindler, S. […]
• Single cell transcriptome analysis of the THY-Tau22 mouse model of Alzheimer’s disease reveals sex-dependent dysregulations
  December 1, 2024
  Single cell transcriptome analysis of the THY-Tau22 mouse model of Alzheimer’s disease reveals sex-dependent dysregulationsAli, M., Garcia, P., Lunkes, L. P., Sciortino, A., Thomas, M., Heurtaux, T., Grzyb, K., Halder, R., Coowar, D., Skupin, A., Buée, L., Blum, D., Buttini, M. & Glaab, E., Dec 2024, In: Cell Death Discovery. 10, 1, 119.Research output: Contribution to journal › Article › peer-review
• Baseline levels and longitudinal changes in plasma Aβ42/40 among Black and white individuals
  December 1, 2024
  Baseline levels and longitudinal changes in plasma Aβ42/40 among Black and white individualsXiong, C., Luo, J., Wolk, D. A., Shaw, L. M., Roberson, E. D., Murchison, C. F., Henson, R. L., Benzinger, T. L. S., Bui, Q., Agboola, F., Grant, E., Gremminger, E. N., Moulder, K. L., Geldmacher, D. S., Clay, O. J., Babulal, G., Cruchaga, C., Holtzman, D. M., Bateman, R. J. & Morris, J. C. & 1 others, Schindler, S. E., Dec 2024, In: Nature communications. 15, 1, 5539.Research output: Contribution to journal › Article › peer-review
• TOPMed imputed genomics enhances genomic atlas of the human proteome in brain, cerebrospinal fluid, and plasma
  December 1, 2024
  TOPMed imputed genomics enhances genomic atlas of the human proteome in brain, cerebrospinal fluid, and plasmaYi, H., Yang, Q., Repaci, C., Lee, C. M., Heo, G., Timsina, J., Gorijala, P., Yang, C., Budde, J., Wang, L., Cruchaga, C. & Sung, Y. J., Dec 2024, In: Scientific data. 11, 1, 387.Research output: Contribution to journal › Article › peer-review