This division focuses on understanding mechanisms of brain function and behavior in the context of psychiatric disease.

Division Director

Alexxai V Kravitz

Alexxai Kravitz

Associate Professor of Psychiatry

Faculty

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Dr. Yun Ju Sung

Yun Ju Sung

Professor of Psychiatry

Dr. Carla Marie Yuede

Carla Yuede

Professor of Psychiatry

Dr. Charles F Zorumski

Charles Zorumski

Samuel B. Guze Professor of Psychiatry

Current Research Publications

  • Early syndecan-4 upregulation predicts cognitive and pathological trajectories in Alzheimer diseaseTarawneh, R., Moulder, K. L., Topouza, D. G., Kar, A., Qian, H. T., Pankratz, V. S., Timsina, J., Franklin, E. E., Schindler, S. E., Perrin, R. J., Ances, B. M., Benzinger, T. L. S., Hassenstab, J., Morris, J. C., Holtzman, D. M. & Cruchaga, C., Dec 2026, In: Alzheimer's Research and Therapy. 18, 1, 152.Research output: Contribution to journal › Article › peer-review
  • Association of LRRK2 p.A419V with Parkinson’s Disease in East Asians and analysis of age at onsetthe Global Parkinson’s Genetics Program (GP2), Dec 2026, In: npj Parkinson's Disease. 12, 1, 51.Research output: Contribution to journal › Article › peer-review
  • Antecedent enhancer activity predicts future susceptibility to seizures in miceBoros, B. D., Gachechiladze, M. A., Guo, J., Galloway, D. A., Mueller, S. M., Shabsovich, M., Yen, A., Chen, X., Cammack, A. J., Shen, T., Mitra, R. D., Dougherty, J. D. & Miller, T. M., Dec 2026, In: Nature communications. 17, 1, 300.Research output: Contribution to journal › Article › peer-review
  • A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a model of frontotemporal dementiaMirfakhar, F. S., Marsh, J. A., Sato, C., Schache, K. J., Minaya, M. A., Dolle, R. E., Pak, S. C., Silverman, G. A., Perlmutter, D. H., Macauley, S. L. & Karch, C. M., Dec 2026, In: Nature communications. 17, 1, 2699.Research output: Contribution to journal › Article › peer-review
  • Persistence of vestibular function in the absence of glutamatergic transmission from hair cellsMukhopadhyay, M., Modgekar, R., Yang-Hood, A., Ohlemiller, K. K., Militchin, V., Xiao, M., Shen, Z., Rensing, N. R., Wong, M., Lee, S. J., Seal, R. P., Holt, J. C., Warchol, M. E., Maloney, S. E., Yuede, C. M., Rutherford, M. A. & Pangrsic, T., Dec 2026, In: Scientific reports. 16, 1, 14550.Research output: Contribution to journal › Article › peer-review