Education & Training
- Ph.D.: Yamagata University, 1989
- M.D.: Yamagata University, 1985
Research Interests
I have over 30 years of experience in investigating synaptic plasticity including long-term potentiation (LTP), long-term depression (LTD) and modulation of hippocampal function by various drugs. We have had long-standing interests in understanding how synaptic function can be modulated under physiological and pathological conditions. Over 25 years I have been collaborating with Dr. Charles F. Zorumski. We have had long-standing interests in understanding how synaptic function can be modulated under physiological and pathological conditions.
Recent Publications
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Effects of acute pro-inflammatory stimulation and 25-hydroxycholesterol on hippocampal plasticity and learning involve NLRP3 inflammasome and cellular stress responses
Izumi, Y., O’Dell, K. A., Mennerick, S. & Zorumski, C., Dec 2025, In: Scientific reports. 15, 1, 6149.
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New directions in neurosteroid therapeutics in neuropsychiatry
Zorumski, C. F., Covey, D. F., Izumi, Y., Evers, A. S., Maguire, J. L. & Mennerick, S. J., May 2025, In: Neuroscience and Biobehavioral Reviews. 172, 106119.
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Proteome-Wide Analysis of Autoantibodies in Open-Angle Glaucoma in Japanese Population: A Pilot Study
Takada, N., Ishikawa, M., Sato, K., Kunikata, H., Ninomiya, T., Hanyuda, A., Fukuda, E., Yamaguchi, K., Ono, C., Kirihara, T., Shintani, C., Tsusu, C., Osanai, A., Goshima, N., Izumi, Y., Zorumski, C. F. & Nakazawa, T., Mar 2025, In: Biomedicines. 13, 3, 718.
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Sertraline modulates hippocampal plasticity via sigma 1 receptors, cellular stress and neurosteroids
Izumi, Y., Reiersen, A. M., Lenze, E. J., Mennerick, S. J. & Zorumski, C. F., Dec 2024, In: Translational psychiatry. 14, 1, 474.
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Glyphosate as a direct or indirect activator of pro-inflammatory signaling and cognitive impairment
Izumi, Y., O’Dell, K. A. & Zorumski, C. F., Oct 2024, In: Neural Regeneration Research. 19, 10, p. 2212-2218 7 p.