Education & Training
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- PhD: the University of Tokyo, Tokyo, Japan, 2013
Major Awards
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- The Japan Neuroscience Society Young Investigator Award, 2021
Research Interests
My research interest lies in understanding how the ovarian hormones estrogen and progesterone modulate social behaviors, anxiety, and mood, both in health and disease. Dysregulated ovarian hormone signaling is thought to be a key factor underlying diverse psychiatric symptoms observed in conditions such as premenstrual syndrome, premenstrual dysphoric disorder, and menopausal syndrome. My team aims to elucidate the neural mechanisms behind ovarian hormone-dependent behavioral changes throughout the lifespan. Towards this goal, I utilize an interdisciplinary approach that includes systems and molecular neurobiological techniques, applied to animal models that exhibit state changes in hormone levels.
Key Publications
- Knoedler JR, Inoue S, Bayless DW, Yang T, Tantry A, Davis CH, Leung NY, Parthasarathy S, Wang G, Alvarado M, Rizvi AH, Fenno LE, Ramakrishnan C, Deisseroth K, Shah NM, (2022 Feb). A functional cellular framework for sex and estrous cycle-dependent gene expression and behavior. Cell. 185(4): 654-671.e22.
Read publication »A functional cellular framework for sex and estrous cycle-dependent gene expression and behavior. - Inoue S, (2022 Mar). Neural basis for estrous cycle-dependent control of female behaviors. Neurosci Res. 176: 1-8.
Read publication »Neural basis for estrous cycle-dependent control of female behaviors. - Inoue S, Yang R, Tantry A, Davis CH, Yang T, Knoedler JR, Wei Y, Adams EL, Thombare S, Golf SR, Neve RL, Tessier-Lavigne M, Ding JB, Shah NM, (2019 Nov). Periodic Remodeling in a Neural Circuit Governs Timing of Female Sexual Behavior. Cell. 179(6): 1393-1408.e16.
Read publication »Periodic Remodeling in a Neural Circuit Governs Timing of Female Sexual Behavior. - Yang T, Yang CF, Chizari MD, Maheswaranathan N, Burke KJ, Borius M, Inoue S, Chiang MC, Bender KJ, Ganguli S, Shah NM, (2017 Aug). Social Control of Hypothalamus-Mediated Male Aggression. Neuron. 95(4): 955-970.e4.
Read publication »Social Control of Hypothalamus-Mediated Male Aggression.