Education & Training
- Postdoctoral Research Associate: Washington University, St. louis, MO, USA, 2023
- PhD in Computational systems biology: University of Luxembourg, Luxembourg., 2019
- MSc in Bioinformatics: Saarland University, Germany, 2014
- MS in Bioinformatics: Government College University, Faisalabad, Pakistan, 2012
- BS(H) in Bioinformatics: Government College University, Faisalabad, Pakistan, 2010
Major Awards
- EURON Mobility Grant, 2019
- Joint Programme – Neurodegenerative Disease (JPND) Doctoral Fellowship, 2015
Research Interests
My research interests lie in the intersection of Bioinformatics and computational systems biology. Currently, I am working on the integrative machine learning analysis of proteomics data from disease-related case-control studies, focusing on biomarker development for the neurodegenerative disorders e.g. Alzheimer’s and Parkinson’s disease.
Key Publications
- Knoedler JR, Inoue S, Bayless DW, Yang T, Tantry A, Davis CH, Leung NY, Parthasarathy S, Wang G, Alvarado M, Rizvi AH, Fenno LE, Ramakrishnan C, Deisseroth K, Shah NM, (2022 Feb). A functional cellular framework for sex and estrous cycle-dependent gene expression and behavior. Cell. 185(4): 654-671.e22.
Read publication »A functional cellular framework for sex and estrous cycle-dependent gene expression and behavior. - Inoue S, (2022 Mar). Neural basis for estrous cycle-dependent control of female behaviors. Neurosci Res. 176: 1-8.
Read publication »Neural basis for estrous cycle-dependent control of female behaviors. - Ali M, Archer DB, Gorijala P, Western D, Timsina J, Fernández MV, Wang TC, Satizabal CL, Yang Q, Beiser AS, Wang R, Chen G, Gordon B, Benzinger TLS, Xiong C, Morris JC, Bateman RJ, Karch CM, McDade E, Goate A, Seshadri S, Mayeux RP, Sperling RA, Buckley RF, Johnson KA, Won HH, Jung SH, Kim HR, Seo SW, Kim HJ, Mormino E, Laws SM, Fan KH, Kamboh MI, Vemuri P, Ramanan VK, Yang HS, Wenzel A, Rajula HSR, Mishra A, Dufouil C, Debette S, Lopez OL, DeKosky ST, Tao F, Nagle MW, , , , , , Hohman TJ, Sung YJ, Dumitrescu L, Cruchaga C, (2023 Apr). Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer disease. Acta Neuropathol Commun. 11(1): 68.
Read publication »Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer disease. - Ali M, Sung YJ, Wang F, Fernández MV, Morris JC, Fagan AM, Blennow K, Zetterberg H, Heslegrave A, Johansson PM, Svensson J, Nellgård B, Lleó A, Alcolea D, Clarimon J, Rami L, Molinuevo JL, Suárez-Calvet M, Morenas-Rodríguez E, Kleinberger G, Haass C, Ewers M, Levin J, Farlow MR, Perrin RJ, , , Cruchaga C, (2022 May). Leveraging large multi-center cohorts of Alzheimer disease endophenotypes to understand the role of Klotho heterozygosity on disease risk. PLoS One. 17(5): e0267298.
Read publication »Leveraging large multi-center cohorts of Alzheimer disease endophenotypes to understand the role of Klotho heterozygosity on disease risk. - Ali M, Huarte OU, Heurtaux T, Garcia P, Rodriguez BP, Grzyb K, Halder R, Skupin A, Buttini M, Glaab E, (2024 Feb). Single-Cell Transcriptional Profiling and Gene Regulatory Network Modeling in Tg2576 Mice Reveal Gender-Dependent Molecular Features Preceding Alzheimer-Like Pathologies. Mol Neurobiol. 61(2): 541-566.
Read publication »Single-Cell Transcriptional Profiling and Gene Regulatory Network Modeling in Tg2576 Mice Reveal Gender-Dependent Molecular Features Preceding Alzheimer-Like Pathologies. - Bigley TM, Xiong M, Ali M, Chen Y, Wang C, Serrano JR, Eteleeb A, Harari O, Yang L, Patel SJ, Cruchaga C, Yokoyama WM, Holtzman DM, (2022 Jan). Murine roseolovirus does not accelerate amyloid-ß pathology and human roseoloviruses are not over-represented in Alzheimer disease brains. Mol Neurodegener. 17(1): 10.
Read publication »Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains.