Additional Titles & Roles
- Assistant Professor of Psychiatry
- Member, Hope Center for Neurological Disorders
- Member, Taylor Family Insititute for Innovvative Psychiatric Research
Education & Training
- Ph.D.: Jawaharlal Nehru University, New Delhi, India, 1997
- M.Sc.: Madurai Kamaraj University, Madurai, India, 1991
- B.Sc: Bangalore University, Bengaluru, India, 1989
Research Interests
Neuroinflammation is thought to play an important role in the pathogenesis of various psychiatric and neurological disorders. We are interested in understanding how cholesterol metabolism influences neuroinflammation.
Key Publications
- Wong MY, Lewis M, Doherty JJ, Shi Y, Cashikar AG, Amelianchik A, Tymchuk S, Sullivan PM, Qian M, Covey DF, Petsko GA, Holtzman DM, Paul SM, Luo W, (2020 Jun). 25-Hydroxycholesterol amplifies microglial IL-1ß production in an apoE isoform-dependent manner. J Neuroinflammation. 17(1): 192.
Read publication »25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner. - Cashikar AG, Shim S, Roth R, Maldazys MR, Heuser JE, Hanson PI, (2014 May). Structure of cellular ESCRT-III spirals and their relationship to HIV budding. Elife. 3:
Read publication »Structure of cellular ESCRT-III spirals and their relationship to HIV budding. - Hanson PI, Cashikar A, (2012 July). Multivesicular body morphogenesis. Annu Rev Cell Dev Biol. 28: 337-62.
Read publication »Multivesicular body morphogenesis. - Ojha J, Masilamoni G, Dunlap D, Udoff RA, Cashikar AG, (2011 Aug). Sequestration of toxic oligomers by HspB1 as a cytoprotective mechanism. Mol Cell Biol. 31(15): 3146-57.
Read publication »Sequestration of toxic oligomers by HspB1 as a cytoprotective mechanism. - Ojha J, Karmegam RV, Masilamoni JG, Terry AV, Cashikar AG, (2011 Feb). Behavioral defects in chaperone-deficient Alzheimer’s disease model mice. PLoS One. 6(2): e16550.
Read publication »Behavioral defects in chaperone-deficient Alzheimer’s disease model mice. - Serio TR, Cashikar AG, Kowal AS, Sawicki GJ, Moslehi JJ, Serpell L, Arnsdorf MF, Lindquist SL, (2000 Aug). Nucleated conformational conversion and the replication of conformational information by a prion determinant. Science. 289(5483): 1317-21.
Read publication »Nucleated conformational conversion and the replication of conformational information by a prion determinant.