Abdallah Eteleeb
Assistant Professor of Psychiatry
- Phone: 314-273-1560
- Email: eteleeb@nospam.wustl.edu
Education & Training
- Instructor in Psychiatry: Washington University, St. Louis, MO, 2022
- Senior Scientist: Washington University, St. Louis, MO, 2021
- Postdoctoral Research Associate: Washington University, St. Louis, MO, 2020
- Ph.D., Computer Science and Engineering (CSE): University of Louisville, Louisville, KY, 2015
- M.S., Information Systems Development: HAN University of Applied Sciences, Arnhem,, The Netherlands, 2005
- B.S., Computer Science: University of Al-Jabal Al-Gharbi, Libya, 1996
Major Awards
- K25 Mentored Quantitative Research Career Development Award – NIA, 2023
- Knight Alzheimer Disease Research Center (ADRC) Research Education Component (REC) Scholar program. Washington University School of Medicine in St. Louis, 2022
- The John Richard Binford Memorial Award. In recognition of the excellence for performance in graduate work., 2015
- The Graduate Dean’s Citations, 2015
- CSE Doctoral Award, 2015
Research Interests
My research interests lie in the field of Bioinformatics and Computational Biology. More specifically, I am interested in the development of computational algorithms and machines learning approaches to integrate and interpret multiple large-scale modalities of “omics” data to better understand the biology of multiple neurodegenerative diseases with more emphasis on Alzheimer’s disease.
Key Publications
- Eteleeb AM, Novotny BC, Tarraga CS, Sohn C, Dhungel E, Brase L, Nallapu A, Buss J, Farias F, Bergmann K, Bradley J, Norton J, Gentsch J, Wang F, Davis AA, Morris JC, Karch CM, Perrin RJ, Benitez BA, Harari O, (2024 Apr). Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer’s disease. PLoS Biol. 22(4): e3002607.
Read publication »Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer’s disease. - Chen HH, Eteleeb A, Wang C, Fernandez MV, Budde JP, Bergmann K, Norton J, Wang F, Ebl C, Morris JC, Perrin RJ, Bateman RJ, McDade E, Xiong C, Goate A, Farlow M, Chhatwal J, Schofield PR, Chui H, Harari O, Cruchaga C, Ibanez L, , (2022 Mar). Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer’s disease. Acta Neuropathol Commun. 10(1): 29.
Read publication »Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer’s disease. - Bhagat R, Minaya MA, Renganathan A, Mehra M, Marsh J, Martinez R, Eteleeb AM, Nana AL, Spina S, Seeley WW, Grinberg LT, Karch CM, (2023 Nov). Long non-coding RNA SNHG8 drives stress granule formation in tauopathies. Mol Psychiatry. 28(11): 4889-4901.
Read publication »Long non-coding RNA SNHG8 drives stress granule formation in tauopathies. - Wani A, Zhu J, Ulrich JD, Eteleeb A, Sauerbeck AD, Reitz SJ, Arhzaouy K, Ikenaga C, Yuede CM, Pittman SK, Wang F, Li S, Benitez BA, Cruchaga C, Kummer TT, Harari O, Chou TF, Schröder R, Clemen CS, Weihl CC, (2021 Jul). Neuronal VCP loss of function recapitulates FTLD-TDP pathology. Cell Rep. 36(3): 109399.
Read publication »Neuronal VCP loss of function recapitulates FTLD-TDP pathology. - Novotny BC, Fernandez MV, Wang C, Budde JP, Bergmann K, Eteleeb AM, Bradley J, Webster C, Ebl C, Norton J, Gentsch J, Dube U, Wang F, Morris JC, Bateman RJ, Perrin RJ, McDade E, Xiong C, Chhatwal J, , , , Goate A, Farlow M, Schofield P, Chui H, Karch CM, Cruchaga C, Benitez BA, Harari O, (2023 May). Metabolomic and lipidomic signatures in autosomal dominant and late-onset Alzheimer’s disease brains. Alzheimers Dement. 19(5): 1785-1799.
Read publication »Metabolomic and lipidomic signatures in autosomal dominant and late-onset Alzheimer’s disease brains. - Sung YJ, Yang C, Norton J, Johnson M, Fagan A, Bateman RJ, Perrin RJ, Morris JC, Farlow MR, Chhatwal JP, Schofield PR, Chui H, Wang F, Novotny B, Eteleeb A, Karch C, Schindler SE, Rhinn H, Johnson ECB, Oh HS, Rutledge JE, Dammer EB, Seyfried NT, Wyss-Coray T, Harari O, Cruchaga C, (2023 Jul). Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer’s disease. Sci Transl Med. 15(703): eabq5923.
Read publication »Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer’s disease.
Funded Research Projects
NIA(PI):Identification and characterization of molecular subtypes of Alzheimer’s disease associated with cognitive function through cross-omics data integration