Division of Basic Science Research

This division focuses on understanding mechanisms of brain function and behavior in the context of psychiatric disease.

Division Director

Alexxai Kravitz

Associate Professor of Psychiatry

• Phone: 314-273-7956
• Email: alexxai@nospam.wustl.edu

Faculty

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Yun Ju Sung

Professor of Psychiatry

• Phone: 314-273-1967
• Email: yunju@wustl.edu

Carla Yuede

Professor of Psychiatry

• Phone: 314-362-9001
• Email: yuedec@wustl.edu

Charles Zorumski

Samuel B. Guze Professor of Psychiatry

• Phone: 314-747-2680
• Email: zorumskc@wustl.edu

Current Research Publications

• Association of LRRK2 p.A419V with Parkinson’s Disease in East Asians and analysis of age at onset
  November 30, 2026
  Association of LRRK2 p.A419V with Parkinson’s Disease in East Asians and analysis of age at onsetthe Global Parkinson’s Genetics Program (GP2), Dec 2026, In: npj Parkinson's Disease. 12, 1, 51.Research output: Contribution to journal › Article › peer-review
• OMG! A proteomic determinant of neurodegenerative resiliency
  November 30, 2026
  OMG! A proteomic determinant of neurodegenerative resiliencyDuggan, M. R., Oh, H. S. H., Frank, P., Gomez, G. T., Zweibaum, D., Cui, Y., Chen, J., Surapaneni, A., Blew, C. O., Dark, H. E., Joynes, C. M., Kandala, S., Bilgel, M., Farinas, A., Erus, G., Tian, Q., Candia, J., Pucha, K. A., Landman, B. A. & Dumitrescu, L. & 36 others, Hohman, T. J., Lewis, A., Moghekar, A., Siavoshi, F., Ali, M., Liu, M., Xu, Y., Western, D., Kaneko, N., Kato, S., Furuichi, M., Shibayama, M., Katsuno, M., Nishita, Y., Otsuka, R., Gottesman, R. F., Dammer, E. B., Seyfried, N. T., Levey, […]
• Antecedent enhancer activity predicts future susceptibility to seizures in mice
  November 30, 2026
  Antecedent enhancer activity predicts future susceptibility to seizures in miceBoros, B. D., Gachechiladze, M. A., Guo, J., Galloway, D. A., Mueller, S. M., Shabsovich, M., Yen, A., Chen, X., Cammack, A. J., Shen, T., Mitra, R. D., Dougherty, J. D. & Miller, T. M., Dec 2026, In: Nature communications. 17, 1, 300.Research output: Contribution to journal › Article › peer-review
• Structure-activity relationships of steroid and sterol neuromodulators on inflammatory markers in a murine microglial cell line
  April 30, 2026
  Structure-activity relationships of steroid and sterol neuromodulators on inflammatory markers in a murine microglial cell lineShu, H. J., Covey, D. F., Zorumski, C. F. & Mennerick, S., May 2026, In: Journal of Steroid Biochemistry and Molecular Biology. 259, 106969.Research output: Contribution to journal › Article › peer-review
• Longitudinal subcortical volume changes and their correlations with multiple PET and fluid biomarkers in dominantly inherited Alzheimer’s disease
  March 31, 2026
  Longitudinal subcortical volume changes and their correlations with multiple PET and fluid biomarkers in dominantly inherited Alzheimer’s diseaseChoo, I. H., Park, H., Gordon, B. A., Bateman, R. J., Bateman, R., Daniels, A. J., Courtney, L., Ziegemeier, A., Skrbec, K., Hellm, C., Martin, M., Ziegemeier, E., Bartzel, J., McDade, E., Libre-Guerra, J. J., Supnet-Bell, C., Xiong, C., Xu, X., Lu, R. & Wang, G. & 106 others, Li, Y., Nie, Y., Gremminger, E., Perrin, R. J., Franklin, E., Ibanez, L., Jerome, G., Stauber, J., Baker, B., Minton, M., Cruchaga, C., Goate, A. M., Renton, A. E., Picarello, D. M., Fulton-Howard, B., […]