Nicole Karcher
Assistant Professor of Psychiatry
- Phone: 314-935-8459
- Email: nkarcher@nospam.wustl.edu
Additional Titles & Roles
- Instructor
Education & Training
- Postdoctoral Research Fellowship: Washington University, St. Louis, MO, 2020
- PhD: University of Missouri, Columbia, MO, 2017
- MA: College of William and Mary, Williamsburg, VA, 2010
- BS: College of William and Mary, Williamsburg, VA, 2008
Major Awards
- NIMH K23 Mentored Patient-Oriented Research Career Development Award, 2020
- NIH Loan Repayment Program Award, 2019
- Mark H. Thelen Outstanding Clinical Graduate Student Award, 2015
Research Interests
My research primarily focuses on understanding the neural, genetic, cognitive, and environmental factors underlying the development and persistence of psychotic-like experiences in childhood and adolescence. My work uses several methodologies, including functional MRI, structural MRI, epidemiological, and genomic approaches to the study of the etiology of psychotic-like experiences. I am also motivated to develop identification and prevention efforts for children and adolescents at risk for the development of psychotic experiences, including efforts to reduce mental health disparities.
Key Publications
- Karcher NR, Niendam TA, Barch DM, (2020 Aug). Adverse childhood experiences and psychotic-like experiences are associated above and beyond shared correlates: Findings from the adolescent brain cognitive development study. Schizophr Res. 222: 235-242.
Read publication »Adverse childhood experiences and psychotic-like experiences are associated above and beyond shared correlates: Findings from the adolescent brain cognitive development study. - Karcher Nicole R.,Barch Deanna M.,;The ABCD study: understanding the development of risk for mental and physical health outcomes;;
Read publication »The ABCD study: understanding the development of risk for mental and physical health outcomes - Karcher Nicole R.,O’Brien Kathleen J.,Kandala Sridhar,Barch Deanna M.,;Resting State Functional Connectivity and Psychotic-Like Experiences in Childhood: Results from the Adolescent Brain Cognitive Development Study;;
Read publication »Resting State Functional Connectivity and Psychotic-Like Experiences in Childhood: Results from the Adolescent Brain Cognitive Development Study - Karcher NR, Barch DM, Demers CH, Baranger DAA, Heath AC, Lynskey MT, Agrawal A, (2019 01). Genetic Predisposition vs Individual-Specific Processes in the Association Between Psychotic-like Experiences and Cannabis Use. JAMA Psychiatry. 76(1): 87-94.
Read publication »Genetic Predisposition vs Individual-Specific Processes in the Association Between Psychotic-like Experiences and Cannabis Use. - Karcher Nicole R.,Barch Deanna M.,Avenevoli Shelli,Savill Mark,Huber Rebekah S.,Simon Tony J.,Leckliter Ingrid N.,Sher Kenneth J.,Loewy Rachel L.,;Assessment of the Prodromal Questionnaire–Brief Child Version for Measurement of Self-reported Psychoticlike Experiences in Childhood;August 2018;;
Read publication »Assessment of the Prodromal Questionnaire–Brief Child Version for Measurement of Self-reported Psychoticlike Experiences in Childhood - Sheffield JM, Karcher NR, Barch DM, (2018 12). Cognitive Deficits in Psychotic Disorders: A Lifespan Perspective. Neuropsychol Rev. 28(4): 509-533.
Read publication »Cognitive Deficits in Psychotic Disorders: A Lifespan Perspective.
Funded Research Projects
NIMH K23: Cross-sectional and longitudinal predictors of psychotic-like experiences in childhood and adolescence
NIMH LRP: Prediction of Distressing Psychotic-Like Experiences in School-Age Children