Frank Saccone

Education & Training

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• Ph.D.: Brown University, 1995
• B.A.: Rensselaer Polytechnic Institute, 1990

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Research Interests

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My work currently focuses on developing data management and web services for biomedical repositories. I currently do this for the NINDS Human Cell and Data Repository (https://nindsgenetics.org) and the NIDA Center for Genetic Studies (https://nidagenetics.org). My previous research areas includes statistical genetics, genome-wide association studies (GWAS) of complex traits, bioinformatics and theoretical mathematics.

Recent Publications

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• Correction to: Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction (Nature Neuroscience, (2021), 24, 10, (1367-1376), 10.1038/s41593-021-00908-3)

  COGA Collaborators, Jan 2025, In: Nature neuroscience. 28, 1, p. 213 1 p.

• Childhood trauma is associated with developmental trajectories of EEG coherence, alcohol-related outcomes, and PTSD symptoms

  COGA Investigators, 2024, (Accepted/In press) In: Psychological medicine.

• The collaborative study on the genetics of alcoholism: Sample and clinical data

  COGA Collaborators, Dick, D. M., Balcke, E., McCutcheon, V., Francis, M., Kuo, S., Salvatore, J., Meyers, J., Bierut, L. J., Schuckit, M., Hesselbrock, V., Edenberg, H. J., Porjesz, B., Porjesz, B., Hesselbrock, V., Foroud, T., Agrawal, A., Dick, D., Hesselbrock, V. & Edenberg, H. J. & 53 others, Foroud, T., Liu, Y., Plawecki, M. H., Kuperman, S., Kramer, J., Porjesz, B., Meyers, J., Kamarajan, C., Pandey, A., Bierut, L., Rice, J., Bucholz, K., Agrawal, A., Schuckit, M., Tischfield, J., Dick, D., Hart, R., Salvatore, J., Almasy, L., Goate, A., Slesinger, P., Scott, D., Bauer, L., Nurnberger, J., Wetherill, L., Xuei, X., Lai, D., O’Connor, S., Chan, G., Chorlian, D. B., Zhang, J., Barr, P., Kinreich, S., Pandey, G., Mullins, N., Anokhin, A., Hartz, S., Johnson, E., McCutcheon, V., Saccone, S., Moore, J., Aliev, F., Pang, Z., Kuo, S., Merikangas, A., Chin, H., Li, T. K., Conneally, P. M., Crowe, R., Reich, W., Kuperman, S., Kramer, J. & Bucholz, K., Oct 2023, In: Genes, Brain and Behavior. 22, 5, e12860.

• The Collaborative Study on the Genetics of Alcoholism: Overview

  COGA Collaborators, Agrawal, A., Brislin, S. J., Bucholz, K. K., Dick, D., Hart, R. P., Johnson, E. C., Meyers, J., Salvatore, J., Slesinger, P., Liu, Y., Plawecki, M. H., Kamarajan, C., Pandey, A., Bierut, L., Rice, J., Schuckit, M., Scott, D., Bauer, L. & Wetherill, L. & 31 others, Xuei, X., Lai, D., O’Connor, S., Chan, G., Chorlian, D. B., Zhang, J., Barr, P., Kinreich, S., Pandey, G., Mullins, N., Anokhin, A., Hartz, S., McCutcheon, V., Saccone, S., Moore, J., Aliev, F., Pang, Z., Kuo, S., Chin, H., Parsian, A., Almasy, L., Foroud, T., Goate, A., Hesselbrock, V., Kramer, J., Kuperman, S., Merikangas, A. K., Nurnberger, J. I., Tischfield, J., Edenberg, H. J. & Porjesz, B., Oct 2023, In: Genes, Brain and Behavior. 22, 5, e12864.

• Changes over time in endorsement of 11 DSM-IV alcohol use disorder (AUD) criteria in young adults with persistent or recurrent AUD in The Collaborative Study on the Genetics of Alcoholism

  The Collaborative Study on the Genetics of Alcoholism (COGA), May 2023, In: Alcohol: Clinical and Experimental Research. 47, 5, p. 919-929 11 p.

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