Rachel Lean
Assistant Professor of Psychiatry
- Phone: 314-273-0854
- Email: rachel.lean@nospam.wustl.edu
Education & Training
- Ph.D.: Washington University in St Louis, 2015
Major Awards
- Honorable Mention 2022 Gerald R. Klerman Award, Brain & Behavior Research Foundation, 2022
- NIMH K01 Research Scientist Development Award, 2020
- NARSAD Young Investigator Award, Brain & Behavior Research Foundation, 2019
Research Interests
Dr. Lean’s research focuses on the neurological and socioenvironmental mechanisms underlying the development of executive dysfunction and psychiatric disorders in at-risk groups of young children, including children born very preterm and children exposed to socioeconomic adversity. Dr. Lean is also interested in the identification of modifiable socioenvironmental factors that may support brain and socioemotional development in at-risk children, with a particular interest in parenting behavior and family functioning. Additionally, she has used structural and diffusion tensor imaging analyses in her research.
Recent Publications
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Neurodevelopmental and Mental Health Outcomes in a National Clinical Sample of Youth with Sex Chromosome Trisomies Compared with Matched Controls
Hall, A., Furniss, A., Tartaglia, N. N., Janusz, J., Wilson, R., Middleton, C., Martin, S., Frazier, J., Martinez-Chadrom, M., Hansen-Moore, J., Ikomi, C., Ross, J., Vogiaski, M. G., Morrow, L., Christakis, D. A., Lean, R. E., Nokoff, N., Pyle, L. & Davis, S. M., Mar 1 2025, In: Journal of Developmental and Behavioral Pediatrics. 46, 2, p. e208-e215
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Associations between Parenting and Cognitive and Language Abilities at 2 Years of Age Depend on Prenatal Exposure to Disadvantage
Leverett, S. D., Brady, R. G., Tooley, U. A., Lean, R. E., Tillman, R., Wilson, J., Ruscitti, M., Triplett, R. L., Alexopoulos, D., Gerstein, E. D., Smyser, T. A., Warner, B., Luby, J. L., Smyser, C. D., Rogers, C. E. & Barch, D. M., Jan 2025, In: Journal of Pediatrics. 276, 114289.
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Adverse Childhood Experiences and Socioemotional Outcomes of Children Born Very Preterm
Bishop, C. L., Lean, R. E., Smyser, T. A., Smyser, C. D. & Rogers, C. E., Jan 2025, In: Journal of Pediatrics. 276, 114377.
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Prenatal social disadvantage is associated with alterations in functional networks at birth
Nielsen, A. N., Triplett, R. L., Bernardez, L. M., Tooley, U. A., Herzberg, M. P., Lean, R. E., Kaplan, S., Meyer, D., Kenley, J. K., Alexopoulos, D., Losielle, D., Latham, A., Smyser, T. A., Agrawal, A., Shimony, J. S., Jackson, J. J., Miller, J. P., Raichle, M. E., Warner, B. B. & Rogers, C. E. & 4 others, , Dec 10 2024, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 50, e2405448121.
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Prenatal exposure to maternal disadvantage-related inflammatory biomarkers: associations with neonatal white matter microstructure
Sanders, A. F. P., Tirado, B., Seider, N. A., Triplett, R. L., Lean, R. E., Neil, J. J., Miller, J. P., Tillman, R., Smyser, T. A., Barch, D. M., Luby, J. L., Rogers, C. E., Smyser, C. D., Warner, B. B., Chen, E. & Miller, G. E., Dec 2024, In: Translational psychiatry. 14, 1, 72.