Education & Training
- Ph.D.: University of Luxembourg, 2019
Major Awards
- EURON Mobility Grant, 2019
- Joint Programme – Neurodegenerative Disease (JPND) Doctoral Fellowship, 2015
Research Interests
My research interests lie in the intersection of Bioinformatics and computational systems biology. Currently, I am working on the integrative machine learning analysis of proteomics data from disease-related case-control studies, focusing on biomarker development for the neurodegenerative disorders e.g. Alzheimer’s and Parkinson’s disease.
Recent Publications
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Multi-cohort cerebrospinal fluid proteomics identifies robust molecular signatures across the Alzheimer disease continuum
Fundació ACE Alzheimer Center Barcelona (FACE), Barcelona-1, Stanford Alzheimer Disease Research Center (Stanford ADRC), Knight Alzheimer Disease Research Center (Knight ADRC) & Alzheimer Disease Neuroimaging Initiative (ADNI), May 7 2025, In: Neuron. 113, 9, p. 1363-1379.e9
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Whole-genome sequencing reveals the impact of lipid pathway and APOE genotype on brain amyloidosis
Patel, M., Pottier, C., Fan, K. H., Cetin, A., Johnson, M., Ali, M., Liu, M., Gorijala, P., Budde, J., Shi, R., Cohen, A. D., Becker, J. T., Snitz, B. E., Aizenstein, H., Lopez, O. L., Morris, J. C., Kamboh, M. I. & Cruchaga, C., Apr 15 2025, In: Human molecular genetics. 34, 8, p. 739-748 10 p.
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Cerebrospinal fluid proteomics identification of biomarkers for amyloid and tau PET stages
Wang, Z., Chen, Y., Gong, K., Zhao, B., Ning, Y., Chen, M., Li, Y., Ali, M., Timsina, J., Liu, M., Cruchaga, C. & Jia, J., Apr 15 2025, In: Cell Reports Medicine. 6, 4, 102031.
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iSODA: A Comprehensive Tool for Integrative Omics Data Analysis in Single- and Multi-Omics Experiments
Olivier-Jimenez, D., Derks, R. J. E., Harari, O., Cruchaga, C., Ali, M., Ori, A., Di Fraia, D., Cabukusta, B., Henrie, A., Giera, M. & Mohammed, Y., Feb 11 2025, In: Analytical Chemistry. 97, 5, p. 2689-2697 9 p.
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A cerebrospinal fluid synaptic protein biomarker for prediction of cognitive resilience versus decline in Alzheimer’s disease
Oh, H. S. H., Urey, D. Y., Karlsson, L., Zhu, Z., Shen, Y., Farinas, A., Timsina, J., Duggan, M. R., Chen, J., Guldner, I. H., Morshed, N., Yang, C., Western, D., Ali, M., Le Guen, Y., Trelle, A., Herukka, S. K., Rauramaa, T., Hiltunen, M. & Lipponen, A. & 18 others, , 2025, (Accepted/In press) In: Nature medicine. e200018.