Education & Training
- Ph.D.: University of Luxembourg, 2019
Major Awards
- EURON Mobility Grant, 2019
- Joint Programme – Neurodegenerative Disease (JPND) Doctoral Fellowship, 2015
Research Interests
Dr. Muhammad Ali is an Assistant Professor in the Department of Psychiatry at Washington University School of Medicine in St. Louis (WashU). His research focuses on identifying biomarkers and therapeutic targets for neurodegenerative diseases, including Alzheimer’s disease (AD), Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and frontotemporal dementia (FTD). His work leverages large-scale, multi-platform proteomic datasets to uncover disease-specific and shared molecular signatures across tissues (cerebrospinal fluid and plasma) and disease stages.
Recent Publications
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High-sensitivity plasma proteomics reveals disease-specific signatures and predictive biomarkers of Alzheimer’s disease phenotypes in a large mixed-dementia cohort
Gong, K., Timsina, J., Ali, M., Chen, Y., Liu, M., Wang, C., Pottier, C., Feld, G. K., Heo, G., Tammie, T. L., Raji, C. A., Ances, B., Gordon, B., Wisch, J. K., Schindler, S., Morris, J., Holtzman, D., Ibanez, L. & Cruchaga, C., Dec 2025, In: Molecular neurodegeneration. 20, 1, 120.
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Author Correction: Shared and disease-specific pathways in frontotemporal dementia and Alzheimer’s and Parkinson’s diseases (Nature Medicine, (2025), 31, 8, (2567-2577), 10.1038/s41591-025-03833-1)
The Global Neurodegeneration Proteomics Consortium (GNPC), Oct 2025, In: Nature medicine. 31, 10, p. 3569 1 p.
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The Global Neurodegeneration Proteomics Consortium: biomarker and drug target discovery for common neurodegenerative diseases and aging
The Global Neurodegeneration Proteomics Consortium (GNPC), Aug 2025, In: Nature medicine. 31, 8, p. 2556-2566 11 p.
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Shared and disease-specific pathways in frontotemporal dementia and Alzheimer’s and Parkinson’s diseases
The Global Neurodegeneration Proteomics Consortium (GNPC), Aug 2025, In: Nature medicine. 31, 8, p. 2567-2577 11 p.
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Novel early-onset Alzheimer-associated genes influence risk through dysregulation of glutamate, immune activation, and intracellular signaling pathways
Alzheimer’s Disease Genetics Consortium (ADGC), Charles F. and Joanne Knight Alzheimer Disease Research Center (Knight-ADRC), Jun 2025, In: Alzheimer’s and Dementia. 21, 6, e70377.