Kathleen Bucholz

Additional Titles & Roles

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• Human Studies Committee, 2000-present
• Executive Director, Family Research Center (formerly the Missouri Family Registry), 2007-2011; 2014-present
• University Sexual Assault Investigation Board, 2016-present

Education & Training

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• Postdoctoral Fellowship: Washington University, St. Louis, MO, 1989
• Predoctoral Fellowship: Washington University, St. Louis, MO, 1986
• Ph.D.: Yale University, 1986
• M.S.: Yale University, 1982
• M.S.: Yale University, 1976
• B.A.: Yale University, 1972

Major Awards

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• Distinguished Faculty Award Postgraduate Education, Washington University, 2017
• Academic Women’s Network Mentor Award, 2010

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Research Interests

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Development and course of alcohol and other substance use disorders in general population, family and twin samples. Gene-environnment influences in SUD development, persistence and remission. Race/Ethnic differences in development of SUDs and other psychiatric disorders. Maternal v paternal influences on offspring psychosocial and SUD and other psychopathological outcomes. Psychiatric assessment and classification.

Recent Publications

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• Clinical, Genomic, and Neurophysiological Correlates of Lifetime Suicide Attempts among Individuals with an Alcohol Use Disorder

  Barr, P. B., Neale, Z., Chatzinakos, C., Schulman, J., Mullins, N., Zhang, J., Chorlian, D. B., Kamarajan, C., Kinreich, S., Pandey, A. K., Pandey, G., Saenz De Viteri, S., Acion, L., Bauer, L., Bucholz, K. K., Chan, G., Dick, D. M., Edenberg, H. J., Foroud, T. & Goate, A. & 10 others, Hesselbrock, V., Johnson, E., Kramer, J. R., Lai, D., Plawecki, M. H., Salvatore, J., Wetherill, L., Agrawal, A., Porjesz, B. & Meyers, J. L., 2025, (Accepted/In press) In: Complex Psychiatry.

• Correction to: Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction (Nature Neuroscience, (2021), 24, 10, (1367-1376), 10.1038/s41593-021-00908-3)

  COGA Collaborators, Jan 2025, In: Nature neuroscience. 28, 1, p. 213 1 p.

• Associations between alcohol use disorder polygenic score and remission in participants from high-risk families and the Indiana Biobank

  Lai, D., Kuo, S. I. C., Wetherill, L., Aliev, F., Zhang, M., Marco, A., Schwantes-An, T. H., Dick, D., Francis, M. W., Johnson, E. C., Kamarajan, C., Kinreich, S., Kuperman, S., Meyers, J., Nurnberger, J. I., Liu, Y., Edenberg, H. J., Porjesz, B., Agrawal, A. & Foroud, T. & 4 others, Schuckit, M., Plawecki, M. H., Bucholz, K. K. & McCutcheon, V. V., Feb 2024, In: Alcohol: Clinical and Experimental Research. 48, 2, p. 283-294 12 p.

• Childhood trauma is associated with developmental trajectories of EEG coherence, alcohol-related outcomes, and PTSD symptoms

  COGA Investigators, 2024, (Accepted/In press) In: Psychological medicine.

• Alcohol milestones and internalizing, externalizing, and executive function: longitudinal and polygenic score associations

  Paul, S. E., Baranger, D. A. A., Johnson, E., Jackson, J. J., Gorelik, A. J., Miller, A. P., Hatoum, A. S., Thompson, W. K., Strube, M., Dick, D. M., Kamarajan, C., Kramer, J. R., Plawecki, M. H., Chan, G., Anokhin, A. P., Chorlian, D. B., Kinreich, S., Meyers, J. L., Porjesz, B. & Edenberg, H. J. & 3 others, Agrawal, A., Bucholz, K. K. & Bogdan, R., 2024, (Accepted/In press) In: Psychological medicine.

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