Abhi Iyer

Education & Training

---

• Ph.D.: Indiana University Indianapolis, 2016
• Ph.D.: Indiana University Indianapolis, 2016
• M.S.: University of Mumbai, 2009
• B.S.: University of Mumbai, 2007

Major Awards

---

• CurePSP Pipeline and Pathway Grant, March 1, 2025 – February 28, 2027
• Knight ADRC REC Scholar, 2025
• George Bartzokis Travel Award, New Vision Research, 11th Annual Charleston Conferences on Alzheimer’s Disease, 2023
• Hope Center for Neurological Disorders and the Washington University Institute of Clinical and Translational Sciences, Just-in-time (JIT) core usage award, 2022
• Indiana University School of Medicine postdoctoral travel grant for the Society for Neuroscience meeting, 2017
• Indiana University School of Medicine graduate student travel grant for the American Association of Immunologists meeting, 2014
• Indiana University Simon Cancer Center Annual Cancer Research Day, Honorable Mention in Basic Science Category by Graduate Student, 2013
• Junior Research Fellowship, Council of Scientific & Industrial Research, India, 2010

View clinician profile

Research Interests

---

Neurodegeneration, Neuroimmunology, microglia, astrocytes

Visit lab website

Recent Publications

---

• Inducible deletion of DGAT1 and 2 from microglia exacerbates neurodegeneration and endolysosomal lipid accumulation in male PS19 mice

  Tabor, G. T., Litvinchuk, A., Chen, Y., Allison, A., Sun, E. W., van Lengerich, B., Davis, S. S., West, E., Schlachetzki, J. C. M., Zeng, C., Hu, H., Lin, P. B., Sharma, P., Chen, X., Parhizkar, S., Song, S., Bao, X., Senthil, L., Iyer, A. K. & You, S. F. & 17 others, Serrano, J. R., Manis, M., Franke, E., Cashikar, A. G., Yuede, C. M., Suh, J. H., Karch, C. M., Folick, A., Koliwad, S. K., Farese, R. V., Walther, T., Huang, E. J., Artyomov, M., Glass, C. K., Di Paolo, G., Ulrich, J. D. & Holtzman, D. M., Jan 27 2026, In: Cell Reports. 45, 1, 116841.

• Cell autonomous microglia defects in a stem cell model of frontotemporal dementia tau

  Iyer, A. K., Vermunt, L., Mirfakhar, F. S., Minaya, M., Acquarone, M., Koppisetti, R. K., Renganathan, A., You, S. F., Danhash, E. P., Schache, K. J., Verbeck, A., Galasso, G., Lee, S. M., Huang, G., Miller, K. J., Marsh, J., Nana, A. L., Spina, S., Seeley, W. W. & Grinberg, L. T. & 4 others, Temple, S., Teunissen, C. E., Sato, C. & Karch, C. M., Oct 2025, In: Molecular Psychiatry. 30, 10, p. 4776-4791 16 p.

• Ms4a4a deficiency ameliorates plaque pathology in a mouse model of amyloid accumulation

  Danhash, E. P., Verbeck, A. C., Western, D., Díaz-Pacheco, A. S., Galasso, G., You, S. F., Huang, G., Starr, E., Miller, N., Nadarajah, C. J., Tiemann Powles, S., Musiek, E. S., Herz, J., Iyer, A. K., Cirrito, J., Cruchaga, C. & Karch, C. M., Aug 2025, In: Alzheimer’s and Dementia. 21, 8, e70580.

• Editorial: Myeloid cells as active players in human neurodegenerative diseases

  Iyer, A. K., Moutinho, M., Ayata, P. & Karahan, H., 2025, In: Frontiers in Neuroscience. 19, 1712394.

• Targeted ASO-mediated Atp1a2 knockdown in astrocytes reduces SOD1 aggregation and accelerates disease onset in mutant SOD1 mice

  Iyer, K., Schoch, K. M., Verbeck, A., Galasso, G., Chen, H., Smith, S., Oldenborg, A., Miller, T. M., Karch, C. M. & Bonni, A., Nov 2023, In: PloS one. 18, 11 November, e0294731.

See more publications

See NCBI publications