Carla Yuede

Additional Titles & Roles

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• Professor of Neuroscience
• Professor of Neurology
• Director, Animal Behavior Core

Education & Training

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• Ph.D.: University of Missouri in St Louis, 2006

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Research Interests

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Alzheimer’s disease, Aß metabolism in the brain, stress and stress-related disorders, mechanisms of learning and memory, behavioral phenotyping of animal models.

Recent Publications

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• Persistence of vestibular function in the absence of glutamatergic transmission from hair cells

  Mukhopadhyay, M., Modgekar, R., Yang-Hood, A., Ohlemiller, K. K., Militchin, V., Xiao, M., Shen, Z., Rensing, N. R., Wong, M., Lee, S. J., Seal, R. P., Holt, J. C., Warchol, M. E., Maloney, S. E., Yuede, C. M., Rutherford, M. A. & Pangrsic, T., Dec 2026, In: Scientific reports. 16, 1, 14550.

• Nicotinamide mononucleotide stimulates the activity of bursting slow-oscillation neurons in the supramammillary nucleus and enhances REM sleep

  Cissé, Y., Brace, C. S., Hsu, V., Yuede, C. M., Rensing, N., Wong, M. & Imai, S. I., May 15 2026, In: iScience. 29, 5, 115741.

• Targeting amyloid-β pathology by chimeric antigen receptor astrocyte (CAR-A) therapy

  Chen, Y., Liu, Y., Nguyen, K., Wu, J., Song, S., Lin, K., Rodrigues, P. F., Du, S., Zhou, C., Xiong, K., Bosch, M., Lin, P. B. C., Khantakova, D., Wu, S., Wu, M., Yuede, C., Holtzman, D. M. & Colonna, M., Mar 5 2026, In: Science. 391, 6789, eads3972.

• Aging reduces motivation through decreased Bdnf expression in the ventral tegmental area

  Lei, H. C., Parker, K. E., Kuo, C. C., Yuede, C. M., McCall, J. G. & Imai, S. I., Mar 2026, In: Molecular Psychiatry. 31, 3, p. 1398-1408 11 p.

• Inducible deletion of DGAT1 and 2 from microglia exacerbates neurodegeneration and endolysosomal lipid accumulation in male PS19 mice

  Tabor, G. T., Litvinchuk, A., Chen, Y., Allison, A., Sun, E. W., van Lengerich, B., Davis, S. S., West, E., Schlachetzki, J. C. M., Zeng, C., Hu, H., Lin, P. B., Sharma, P., Chen, X., Parhizkar, S., Song, S., Bao, X., Senthil, L., Iyer, A. K. & You, S. F. & 17 others, Serrano, J. R., Manis, M., Franke, E., Cashikar, A. G., Yuede, C. M., Suh, J. H., Karch, C. M., Folick, A., Koliwad, S. K., Farese, R. V., Walther, T., Huang, E. J., Artyomov, M., Glass, C. K., Di Paolo, G., Ulrich, J. D. & Holtzman, D. M., Jan 27 2026, In: Cell Reports. 45, 1, 116841.

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