| 1918-1938 | Dr. Sidney Schwab headed the Department of Neurology and Psychiatry (a “subdepartment” of the Department of Medicine). |
| 1938-1942 | Dr. Rioch headed the newly created Department of Neuropsychiatry. Dr. Whitehorn was appointed Professor of Psychiatry and had a leading role in teaching psychiatry. |
| 1942-1963 | Dr. Edwin Gildea headed the Department for 21 years. In 1955, the Department was renamed the Department of Psychiatry and Neurology. |
| 1963-1975 | Dr. Eli Robins headed the Department of Psychiatry, which became an independent department in 1963. |
| 1975-1989 | Dr. Samuel Guze headed the Department of Psychiatry. |
| 1989-1993 | Dr. C. Robert Cloninger headed the Department of Psychiatry. |
| 1993-1997 | Dr. Samuel Guze headed the Department of Psychiatry. |
| 1997- 2022 | Dr. Charles Zorumski headed the Department of Psychiatry. |
| 2022-current | Dr. Eric Lenze headed the Department of Psychiatry. |