Lari Niko-Petteri Nykanen

Education & Training

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• Ph.D.: University of Helsinki, 2016
• M.S.: University of Helsinki, 2012

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Recent Publications

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• Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer’s disease

  Wang, L., Nykänen, N. P., Western, D., Gorijala, P., Timsina, J., Li, F., Wang, Z., Ali, M., Yang, C., Liu, M., Brock, W., Marquié, M., Boada, M., Alvarez, I., Aguilar, M., Pastor, P., Ruiz, A., Puerta, R., Orellana, A. & Rutledge, J. & 13 others, Oh, H., Greicius, M. D., Le Guen, Y., Perrin, R. J., Wyss-Coray, T., Jefferson, A., Hohman, T. J., Graff-Radford, N., Mori, H., Goate, A., Levin, J., Sung, Y. J. & Cruchaga, C., Dec 2024, In: Molecular neurodegeneration. 19, 1, 1.

• Proteome wide association studies of LRRK2 variants identify novel causal and druggable proteins for Parkinson’s disease

  Dominantly Inherited Alzheimer Network (DIAN) Consortia, Dec 2023, In: npj Parkinson’s Disease. 9, 1, 107.

• Pleiotropic effect of LRRK2 on Parkinson-associated proteins and processing of pathological alpha-synuclein in myeloid cells

  Nykanen, L.N.-P., Yang, C., Harari, O., Davis, G., Cruchaga, C. & Benitez Viloria, B. A., Dec 2022, In: Alzheimer’s and Dementia. 18, S4, e063954.

• Exosomal secretion of α-synuclein as protective mechanism after upstream blockage of macroautophagy

  Fussi, N., Höllerhage, M., Chakroun, T., Nykänen, N. P., Rösler, T. W., Koeglsperger, T., Wurst, W., Behrends, C. & Höglinger, G. U., Jul 1 2018, In: Cell Death and Disease. 9, 7, 757.

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