Blanche F. Ittleson Professor of Psychiatry and Pediatrics
Director, William Greenleaf Eliot Division of Child & Adolescent Psychiatry
Associate Director of the Intellectual and Developmental Disability Research Center
Co-Director of the Center for Violence and Injury Prevention - George Warren Brown School of Social Work
Education and Training
B.A.: Cornell University, Ithaca, New York, 1984
Medical Degree: Washington University School of Medicine, St. Louis, Missouri, 1988
Residency: Pediatrics, Albert Einstein College of Medicine, Bronx, New York, 1990
Residency: Psychiatry, Albert Einstein College of Medicine, Bronx, New York, 1992
Fellowship: Child Psychiatry, Albert Einstein College of Medicine, Bronx, New York, 1993
Research Fellow: Psychiatric Epidemiology, Washington University School of Medicine, St. Louis, Missouri, 1996
Listed in Best Doctors in America, 2002-2010 (Best Doctors, Inc) & Best Doctors of St. Louis, 2009-2012 (St. Louis Magazine)
Gubernational Appointment to the Mental Health Commission, State of Missouri, 2003-2007
Distinguished Service Teaching Award (Clinical Teacher of the Year) WUSM, 2003
Child Advocate of the Year, St. Louis Area Council on Child Abuse and Neglect, 2007
Guardian Angel Award, Family Support Network, St. Louis Missouri, 2008
Areas of Clinical Interest
Disorders of social development in children (infancy through early adulthood) including autism, abnormally aggressive behavior, personality disorder; psychiatric complications of neurodevelopmental disorders; treatment-refractory child psychiatric conditions.
Areas of Research Interests
Longitudinal studies of the development, life course and genetic structure of autistic syndromes.
Prevention of Child Maltreatment and its consequences, including disruptive behavior disorders of childhood.
Parenting Education for families at risk.
Studies of internal working models (mental representations) of attachment.
Special Populations, Data Sets and Facilities
Active collaborations with health, education, and social service agencies throughout metropolitan St. Louis to identify and support children at risk for child maltreatment and its consequences.
Clinical sample of 300 sibling pairs concordant and discordant for autism, enrolled in a longitudinal study of social development.
Collaboration with the Autism Genetic Resource Exchange (AGRE) to acquire quantitative trait data on all members of nuclear families affected by autism, for the purpose of identifying susceptibility genes.
Collaboration with the Interactive Autism Network (IAN) Volunteer register to acquire autistic trait data on over 10,000 families affected by autism spectrum conditions.
Constantino JN, Hashemi N, Solis E, Alon T, Haley S, McClure S, Nordlicht N, Constantino MA, Elmen J, Carlson VK (2001 Dec). Supplementation of urban home visitation with a series of group meetings for parents and infants: results of a "real-world" randomized, controlled trial. Child Abuse Negl. 25(12): 1571-81. Full Article ->
Constantino JN, Todd RD (2003 May). Autistic traits in the general population: a twin study. Arch Gen Psychiatry. 60(5): 524-30. Full Article ->
Jonson-Reid M, Presnall N, Drake B, Fox L, Bierut L, Reich W, Kane P, Todd RD, Constantino JN (2010 Apr). Effects of child maltreatment and inherited liability on antisocial development: an official records study. J Am Acad Child Adolesc Psychiatry. 49(4): 321-32; quiz 431. Full Article ->
Constantino JN, Zhang Y, Frazier T, Abbacchi AM, Law P (2010 Nov). Sibling recurrence and the genetic epidemiology of autism. Am J Psychiatry. 167(11): 1349-56. Full Article ->
Constantino JN, Todorov A, Hilton C, Law P, Zhang Y, Molloy E, Fitzgerald R and Geschwind D. Autism recurrence in half siblings: strong support for genetic mechanisms of transmission in ASD. Mol Psychiatry. 2012 Feb 28 [Epub ahead of print]. Full Article ->
Funded Research Projects
CDC (PI): Metropolitan St. Louis Autism & Developmental Disabilities Surveillance & Epidemiology
NICHD (PI): Autistic Traits: Life Course & Genetic Structure
NIMH (Site PI): ACE Network: A Comprehensive Approach to the Identification of Autism Susceptibility Genes
CDC (Co-Director): Brown Center for Violence and Injury Prevention
NICHD (Associate Director): Intellectual and Developmental Disabilities Research Centers
St. Louis County Children’s Service Fund (PI): Comprehensive Approach to Unmet Mental Health Needs of Preschool Children in Foster Care, Phase 1
NICHD (PI): Early Quantitative Characterization of Reciprocal Social Behavior