Current
Position
Associate Professor of Psychiatry,
Neurology, Neurobiology, and Radiology
University Roles
Alternate, Washington University School of Medicine Human Studies Committee (IRB)
Coursemaster, third year medical student psychiatry clerkships
Education and Training
B.S., mathematics: Brigham Young University, Provo, Utah, 1986
Medical Degree: Duke University School of Medicine, Durham, North Carolina, 1990
Residency: Psychiatry, Barnes-Jewish Hospital, Washington University, St. Louis, Missouri, 1994
Fellowship: Movement Disorders and Neuroimaging, Washington University, St. Louis, Missouri, 1996
Major Awards
Certification in Behavioral Neurology and Neuropsychiatry, United Council for Neurologic Subspecialties (UCNS), 2006
Named a Fellow of the American Neuropsychiatric Association, 2006
Hope Award from the St. Louis chapter of the HDSA (Huntington Disease Society of America), 2006
Listed in Americas Best Doctors, 2005-2008
American College of Neuropsychopharmacology (ACNP) / Bristol-Myers Squibb Travel Award, 2001
NARSAD Young Investigator Awards, 1996 and 1999
Upjohn Resident Research Award, Washington University Department of Psychiatry, 1994
Southern Psychiatric Association Annual Award for Psychiatrists in Training, 1993
Mead Johnson Fellow in Academic Psychiatry, Association for Academic Psychiatry, 1993
Areas of Clinical Interest
Tourette syndrome (TS), tic disorders, Huntington's disease, tardive dyskinesia, catatonia, neuropsychiatry of Parkinson's disease and dystonia, psychogenic or atypical movement disorders
Areas of Research Interests
Functional neuroimaging with dopaminergic challenges using PET and fMRI, including:
= Methods development for quantitative pharmacologic fMRI
= Neuroimaging in Tourette syndrome (TS) and Parkinson disease (PD)
Neuropsychiatric treatment studies in TS, and in PD with depression or psychosis
Key Publications
Hershey T, Black KJ, Hartlein JM, Barch DM, Braver TS, Carl JL, Perlmutter JS (2004 May 1). Cognitive-pharmacologic functional magnetic resonance imaging in tourette syndrome: a pilot study. Biol Psychiatry. 55(9): 916-25. Full Article ->
Black KJ, Hershey T, Hartlein JM, Carl JL, Perlmutter JS (2005 Mar). Levodopa challenge neuroimaging of levodopa-related mood fluctuations in Parkinson's disease. Neuropsychopharmacology. 30(3): 590-601. Full Article ->
Marsh L, McDonald WM, Cummings J, Ravina B, NINDS/NIMH Work Group on Depression and Parkinson's Disease (2006 Feb). Provisional diagnostic criteria for depression in Parkinson's disease: report of an NINDS/NIMH Work Group. Mov Disord. 21(2): 148-58. Full Article ->
Gordon M, Markham J, Hartlein JM, Koller JM, Loftin S, Black KJ (2007 Jan 30). Intravenous levodopa administration in humans based on a two-compartment kinetic model. J Neurosci Methods. 159(2): 300-7. Full Article ->
Wang L, Lee DY, Bailey E, Hartlein JM, Gado MH, Miller MI, Black KJ (2007 Feb 28). Validity of large-deformation high dimensional brain mapping of the basal ganglia in adults with Tourette syndrome. Psychiatry Res. 154(2): 181-90. Full Article ->
Black KJ (2008 Jan-Feb). "Stop doing that"! Recognizing and managing tics. Mo Med. 105(1): 53-6. Full Article ->
Funded Research Projects
NIMH(PI):Dopaminergic Effects on Cortical Function in Tourette's
NINDS(Key Personnel):Mapping Mood in the Subthalamic Nucleus in PD
NIDDK(Key Personnel):Glycemic Control, Brain Structure and Cognition in Youth with T1DM
Tourette Syndrome Association(PI):Finding Tics in the Community Without Putting a Doctor on Every Corner
NIMH(PI):Quantitative Dopamine Receptor Pharmacodynamics from fMRI
Synosia Therapeutics(PI):A randomized, double-blind, placebo-controlled, two-way cross-over study to explore the effects of 7 days dosing with SYN115 20 mg p.o. BID or 60 mg p.o. BID on clinical and fMRI response to intravenous levodopa in patients with mild to moderate Parkinsons disease
NCRR(Key Personnel):Washington University Institute of Clinical and Translational Sciences - Brain, Behavior and Performance Unit (Perlmutter, PI)