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Kathleen Keenan Bucholz, PhD

Kathleen Keenan Bucholz, PhD Current Position
Professor of Psychiatry

University Roles
Human Studies Committee #3A, 7/2000-present; Course master, 4 week epidemiology series for Psychiatry residents, 1996-present; Director, Missouri Family Registry,1/2007 -present

Education and Training
Undergraduate:
1969-1972 B.A., American Studies, Yale College, New Haven, CT
Graduate:
1974-1976 M.P.H., Hospital Administration, Yale University, New Haven, CT
1980-1982 M.Phil, Epidemiology, Yale University, New Haven, CT
1984-1986 Predoctoral fellow in psychiatric epidemiology, Washington University School of Medicine, St. Louis, MO
1980-1986 Ph.D., Epidemiology, Yale University, New Haven, CT
1990 M.P.E., Psychiatry Epidemiology,
Washington University School of Medicine, St. Louis, MO
Post doctoral:
1986-89 Postdoctoral Fellow in Psychiatric Epidemiology, Department of Psychiatry, Washington University School of Medicine, St. Louis, MO


Areas of Research Interests
1. development and course of alcohol use, abuse and dependence in general population, family and twin samples
2. effects of alcohol dependence on health services use and costs
3. gene-environnment interaction in SUD development, persistence and remission
4. psychiatric assessment and classification

SPECIAL POPULATIONS, DATA SETS AND FACILITIES:
Data sets available at the CID building include ECA data and follow-up data; COGA data; adult twin data; adolescent and young adult twin data; adult male Vietnam-era veteran twin data; offspring of twin data; and MOFAM data.


Key Publications
Bucholz KK, Heath AC, Reich T, Hesselbrock VM, Kramer JR, Nurnberger JI Jr, Schuckit MA (1996 Nov). Can we subtype alcoholism? A latent class analysis of data from relatives of alcoholics in a multicenter family study of alcoholism. Alcohol Clin Exp Res. 20(8): 1462-71.  Full Article ->

Bucholz KK, Heath AC, Madden PA (2000 Jun). Transitions in drinking in adolescent females: evidence from the Missouri adolescent female twin study. Alcohol Clin Exp Res. 24(6): 914-23.  Full Article ->

Grant JD, Scherrer JF, Lynskey MT, Lyons MJ, Eisen SA, Tsuang MT, True WR, Bucholz KK (2006 Jan). Adolescent alcohol use is a risk factor for adult alcohol and drug dependence: evidence from a twin design. Psychol Med. 36(1): 109-18.  Full Article ->

Scherrer JF, Grant JD, Duncan AE, Pan H, Waterman B, Jacob T, Haber JR, True WR, Heath AC, Bucholz KK (2008 Oct). Measured environmental contributions to cannabis abuse/dependence in an offspring of twins design. Addict Behav. 33(10): 1255-66.  Full Article ->

Edens EL, Glowinski AL, Grazier KL, Bucholz KK (2008 Jan 11). The 14-year course of alcoholism in a community sample: do men and women differ? Drug Alcohol Depend. 93(1-2): 1-11.  Full Article ->


Funded Research Projects
NIAAA(Key Personnel):Midwest Alcoholism Research Center: Genetic Epidemiology of Alcoholism & Comorbidity
NIAAA(PI):Alcoholism: Epidemiologic High Risk Family Study - MOFAM
NIDA(PI):Gene Environment in Outcomes of Offspring of Twins with Substance Use Disorders
NIAAA(PI):A New Annual Alcohol Research Form: Guze Symposium