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Kathleen Keenan Bucholz, PhD

Current Position
Professor of Psychiatry

University Roles
Human Studies Committee, 7/2000-present; Director, Missouri Family Registry,1/2007 - 2011; 2014-.

Education and Training
1969-1972 B.A., American Studies, Yale College, New Haven, CT
1974-1976 M.P.H., Hospital Administration, Yale University, New Haven, CT
1980-1982 M.Phil, Epidemiology, Yale University, New Haven, CT
1984-1986 Predoctoral fellow in psychiatric epidemiology, Washington University School of Medicine, St. Louis, MO
1980-1986 Ph.D., Epidemiology, Yale University, New Haven, CT
1990 M.P.E., Psychiatry Epidemiology,
Washington University School of Medicine, St. Louis, MO
Post doctoral:
1986-89 Postdoctoral Fellow in Psychiatric Epidemiology, Department of Psychiatry, Washington University School of Medicine, St. Louis, MO

Major Awards
Academic Women’s Network Mentor Award, 2010

Areas of Research Interests
Development and course of alcohol and other substance use disorders in general population, family and twin samples.

Gene-environnment interaction in SUD development, persistence and remission.

Ethnic differences in psychiatric disorders.

Psychiatric assessment and classification.

Data sets available include longitudinal data from adolescents and young adults from high risk general population (MOFAM) and treatment (COGA) samples, longitudinal data from adolescent and young adult offspring of twin fathers with alcoholism and other drug dependence, adult male Vietnam-era veteran twin data; national data sets (NESARC, NLAES, Add-Health).

Key Publications
McCutcheon VV, Scherrer JF, Grant JD, Xian H, Haber JR, Jacob T, Bucholz KK (2013 Feb 1). Parent, sibling and peer associations with subtypes of psychiatric and substance use disorder comorbidity in offspring. Drug Alcohol Depend. 128(1-2): 20-9.  Full Article ->

Duncan AE, Lessov-Schlaggar CN, Sartor CE, Bucholz KK (2012 Sep 1). Differences in time to onset of smoking and nicotine dependence by race/ethnicity in a Midwestern sample of adolescents and young adults from a high risk family study. Drug Alcohol Depend. 125(1-2): 140-5.  Full Article ->

Grant JD, Scherrer JF, Lynskey MT, Lyons MJ, Eisen SA, Tsuang MT, True WR, Bucholz KK (2006 Jan). Adolescent alcohol use is a risk factor for adult alcohol and drug dependence: evidence from a twin design. Psychol Med. 36(1): 109-18.  Full Article ->

Scherrer JF, Grant JD, Duncan AE, Pan H, Waterman B, Jacob T, Haber JR, True WR, Heath AC, Bucholz KK (2008 Oct). Measured environmental contributions to cannabis abuse/dependence in an offspring of twins design. Addict Behav. 33(10): 1255-66.  Full Article ->

Edens EL, Glowinski AL, Grazier KL, Bucholz KK (2008 Jan 11). The 14-year course of alcoholism in a community sample: do men and women differ? Drug Alcohol Depend. 93(1-2): 1-11.  Full Article ->

Glass JE, Bucholz KK (2011 Jul 1). Concordance between self-reports and archival records of physician visits: a case-control study comparing individuals with and without alcohol use disorders in the community. Drug Alcohol Depend. 116(1-3): 57-63.  Full Article ->

Funded Research Projects
NIMH(Significant Contributor):Prescription Opioid Analgesics and Risk of Major Depression
American Cancer Society(Key Personnel):Nicotine Withdrawal and Depression and Effects on Smoking Persistence
NIDA(Significant Contributor):Cannabis, Depression and Suicidal Thoughts and Behaviors
NIAAA(Key Personnel):Age at First Drink and Alcoholism: Intersection of Genes and Environment
NIAAA(Significant Contributor):Collaborative Study on the Genetics of Alcoholism (COGA)
NIAAA(Significant Contributor):Distinctions Between Black and White Young Women in the Course of Alcohol Use