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Igor Zwir, PhD

Current Position
Assistant Professor Psychiatry

Education and Training
University of Buenos Aires, Argentina BC 1992 Computer Science
University of Buenos Aires, Argentina M.Sc. 1997 Artificial Intelligence
University of Granada, Spain / SRI International Ph.D. 2001 Computer Science

Major Awards
Best PhD Thesis, University of Granada (2001); Howard Hughes Medical Institute award for five and ten years of continuous and successful research in Microbiology (2007 and 2011); and Klerman Award in Clinical Psychiatry Research (NARSAD) for the Schizophrenia Risk Function (Dr. de Erausquin, Dr. I. Zwir, et al) (2008)

Areas of Research Interests
Machine Learning
Computational Biology
Mental Disorders

Key Publications
Arnedo J, Svrakic DM, Del Val C, Romero-Zaliz R, Hern├índez-Cuervo H, Molecular Genetics of Schizophrenia Consortium, Fanous AH, Pato MT, Pato CN, de Erausquin GA, Cloninger CR, Zwir I (2015 Feb 1). Uncovering the hidden risk architecture of the schizophrenias: confirmation in three independent genome-wide association studies. Am J Psychiatry. 172(2): 139-53.  Full Article ->

Arnedo J, Mamah D, Baranger DA, Harms MP, Barch DM, Svrakic DM, de Erausquin GA, Cloninger CR, Zwir I (2015 Jul 4). Decomposition of brain diffusion imaging data uncovers latent schizophrenias with distinct patterns of white matter anisotropy. Neuroimage. 12043-54.  Full Article ->

Zwir I, Shin D, Kato A, Nishino K, Latifi T, Solomon F, Hare JM, Huang H, Groisman EA (2005 Feb 22). Dissecting the PhoP regulatory network of Escherichia coli and Salmonella enterica. Proc Natl Acad Sci U S A. 102(8): 2862-7.  Full Article ->

Arnedo J, del Val C, de Erausquin GA, Romero-Zaliz R, Svrakic D, Cloninger CR, Zwir I (2013 Jul). PGMRA: a web server for (phenotype x genotype) many-to-many relation analysis in GWAS. Nucleic Acids Res. 41(Web Server issue): W142-9.  Full Article ->

Zwir I, Yeo WS, Shin D, Latifi T, Huang H, Groisman EA (2014 Oct 7). Bacterial nucleoid-associated protein uncouples transcription levels from transcription timing. MBio. 5(5): e01485-14.  Full Article ->

Svrakic DM, Zorumski CF, Svrakic NM, Zwir I, Cloninger CR (2013 Mar). Risk architecture of schizophrenia: the role of epigenetics. Curr Opin Psychiatry. 26(2): 188-95.  Full Article ->