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Michael Gaffrey, PhD

Current Position
Assistant Professor of Psychiatry

University Roles
Director, Early Preventive Intervention Clinic

Education and Training
2009 PHD: University of Wisconsin, Milwaukee, Wisconsin
2004 MA: San Diego State University, San Diego, California
1997 BA: University of Wisconsin, Madison, Wisconsin

Major Awards
2014-2016 Fellow, ZERO-TO-THREE Leadership Development Institute
2012-2016 NIMH Mentored Patient-Oriented Research Career Development Award
2012-2014 NIMH Career Development Institute for Psychiatric Research Awardee
2010-2012 Klingenstein Third Generation Foundation Fellow in Childhood Depression

Areas of Clinical Interest
Infant and early childhood mental health

Naturalistic Developmental Behavioral Interventions for Autism Spectrum Disorder

Preventive intervention for infants, toddlers and their families

Pediatric neuropsychology

Areas of Research Interests
Currently, Dr. Gaffrey is directing research focused on the use of brain imaging techniques to improve our understanding of early emotional development in both healthy preschoolers and those at increased risk for depression. It is Dr. Gaffrey’s hope that the tools of neuroscience will provide unique insight into the early development of depression and lead to the development of novel interventions that prevent its occurrence. In addition, he is actively involved in developing an applied line of research that integrates neuroscience into the study of preventive interventions for autism spectrum disorder during infancy. In the future, Dr. Gaffrey intends to continue pursuing the integration of basic and applied research as a means to not only more effectively help infants and families who are at risk for poor outcomes but also to promote the well-being of infants and families through systems change more generally.

Key Publications
Gaffrey MS, Luby JL, Belden AC, Hirshberg JS, Volsch J, Barch DM (2011 Mar). Association between depression severity and amygdala reactivity during sad face viewing in depressed preschoolers: an fMRI study. J Affect Disord. 129(1-3): 364-70.  Full Article ->

Gaffrey, M.S., Luby, J.L., Repovš, G., Belden, A.C., Botteron, K.N., Luking, K.R., & Barch, D.M. (2010). Subgenual cingulate connectivity in children with a history of preschool-depression. NeuroReport, 21(18), 1182-1188.  Full Article ->

Gaffrey MS, Belden AC, Luby JL (2011 Oct). The 2-week duration criterion and severity and course of early childhood depression: implications for nosology. J Affect Disord. 133(3): 537-45.  Full Article ->

Gaffrey, M.S., Luby, J.L., Botteron, K., Repovš, G., & Barch, D.M. (2012 Apr). Default Mode Network connectivity in children with a history of preschool-depression. J Child Psychol and Psychiatry.   Full Article ->

Gaffrey MS, Luby JL, Barch DM (2012 Jun 30). Towards the study of functional brain development in depression: An Interactive Specialization approach. Neurobiol Dis.   Full Article ->

Gaffrey MS, Barch DM, Singer J, Shenoy R, Luby JL (2013 Jul). Disrupted amygdala reactivity in depressed 4- to 6-year-old children. J Am Acad Child Adolesc Psychiatry. 52(7): 737-46.  Full Article ->

Funded Research Projects
Klingenstein Third Generation Foundation Fellowship (PI): Neural circuitry of Preschool Onset Major Depressive Disorder

McDonnell Center for Systems Neuroscience (PI): Functional brain activity and organization in preschool age children with a history of maternal depression

McDonnell Center for Systems Neuroscience (Co-I): Baby on the Brain: Neurobiological mechanisms of caregiving associated with postpartum depression

NIMH K23 (PI): Functional brain network development in early childhood depression

NIMH R01 (PI): Neurodevelopmental trajectories of reward processing in very early emerging risk for depression