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Christina Lessov-Schlaggar, PhD

Current Position
Associate Professor of Psychiatry

University Roles
Research, mentorship

Education and Training
BS, Molecular Biology & Biochemistry, Western Washington University, Bellingham, WA
PhD, Behavioral Neuroscience, Oregon Health & Science University, Portland, OR
Postdoctoral training, Psychiatric Genetics, Washington University School of Medicine, St. Louis, MO

Areas of Research Interests
Developmental cognitive neuroscience; brain mechanisms of addiction; genetic and environmental influences on substance use behavior; neighborhood factors and substance use; twin and family studies; assessing dementia in individuals with intellectual disability

Key Publications
Lessov-Schlaggar CN, Kristjansson SD, Bucholz KK, Heath AC, Madden PA, (2012 Sep). Genetic influences on developmental smoking trajectories. Addiction. 107(9): 1696-704.  Full Article ->

Lessov-Schlaggar CN, Lepore RL, Kristjansson SD, Schlaggar BL, Barnes KA, Petersen SE, Madden PA, Heath AC, Barch DM, (2013 Jan). Functional neuroimaging study in identical twin pairs discordant for regular cigarette smoking. Addict Biol. 18(1): 98-108.  Full Article ->

Power JD, Schlaggar BL, Lessov-Schlaggar CN, Petersen SE, (2013 Aug). Evidence for hubs in human functional brain networks. Neuron. 79(4): 798-813.  Full Article ->

Lian M, Madden PA, Lynskey MT, Colditz GA, Lessov-Schlaggar CN, Schootman M, Heath AC, (2016 April). Geographic Variation in Maternal Smoking during Pregnancy in the Missouri Adolescent Female Twin Study (MOAFTS). PLoS ONE. 11(4): e0153930.  Full Article ->

Heath AC, Lessov-Schlaggar CN, Lian M, Miller R, Duncan AE, Madden PA, (2016 Sep). Research on Gene-Environment Interplay in the Era of "Big Data". J Stud Alcohol Drugs. 77(5): 681-3.  Full Article ->

Lessov-Schlaggar CN, Rubin JB, Schlaggar BL, (2016 June). The Fallacy of Univariate Solutions to Complex Systems Problems. Front Neurosci. 10: 267.  Full Article ->

Funded Research Projects
NIMH(Significant Contributor):NMDA Receptor Antagonist Nitrous Oxide Targets Affective Brain Circuits
NARSAD(Significant Contributor):Nitrous Oxide for Treatment Resistant Depression: Optimizing Dosing Strategies
NICHD(Significant Contributor):Washington University Intellectual and Developmental Disabilities Research Center
NIDA(Significant Contributor):3/13 ABCD-USA Consortium: Twin Research Project
American Foundation for Suicide Prevention(Significant Contributor):Adjunctive Nitrous Oxide for Acute Suicidal Ideation in Unipolar Depressed Hospitalized Patients
NIDA(Significant Contributor): Multilevel Interplays in the Development of Tobacco Dependence
NINDS(Significant Contributor):Parkinson Disease Clinical Subtypes: Validation, Clinical Utility, and Biological Correlates